SCHEMBL6795867

SCHEMBL6795867

O=C(Nc1cccc([N+](=O)[O-])c1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.85
KMT2A Q03164 9/20 0.85
MAPT P10636 5/20 0.85
POLB P06746 4/20 0.85
BLM P54132 1/20 0.85
NPC1 O15118 4/20 0.75
RAB9A P51151 4/20 0.75
ALDH1A1 P00352 2/20 0.72
LMNA P02545 1/20 0.72
NFKB1 P19838 1/20 0.72
NFKB2 Q00653 1/20 0.72
RELA Q04206 1/20 0.72
SMN1; SMN2 Q16637 1/20 0.72
MITF O75030 1/20 0.69
CYP3A4 P08684 2/20 0.69
CYP2C9 P11712 2/20 0.69
CYP2C19 P33261 1/20 0.69
DDX3X O00571 1/20 0.69
HTT P42858 1/20 0.69
CTDSP1 Q9GZU7 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL30758621 0.98 MEN1 (0.83) MEN1KMT2AMAPTPOLBBLM
SCHEMBL9329754 0.94 MEN1 (0.85) MEN1KMT2AMAPTPOLBBLM
SCHEMBL10943066 0.92 KMT2A (0.94) MEN1KMT2AMAPTPOLBBLM
SCHEMBL18300094 0.92 MEN1 (1.00) MEN1KMT2AMAPTPOLBBLM
SCHEMBL32690121 0.92 MEN1 (1.00) MEN1KMT2AMAPTPOLBBLM
SCHEMBL10090738 0.91 KMT2A (0.72) MEN1KMT2AMAPTPOLBBLM
SCHEMBL9800017 0.91 GAA (0.77) MEN1KMT2AMAPTPOLBBLM
SCHEMBL299879 0.91 KMT2A (0.88) MEN1KMT2AMAPTPOLBBLM
SCHEMBL30868371 0.91 KMT2A (0.88) MEN1KMT2AMAPTPOLBBLM
SCHEMBL8710919 0.91 MEN1 (0.80) MEN1KMT2AMAPTPOLBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220039381-A1 FUNGICIDE ENHANCERS EFFECTIVE FOR TREATING PLANTS INFECTED WITH FUNGAL PATHOGENS UNIV TEXAS (US) 2022-02-10 US claimed
CN-1235886-C Method for preparing sulfhydyl-(m-benzamido) phenyl tetrazole HUAFENG CHEMICAL CO LTD NANTON (CN) 2006-01-11 CN claimed
CN-1155278-A Arylthio compounds as antibacteral and antiviral agents WARNER LAMBERT CO (US) 1997-07-23 CN claimed
US-12213482-B2 Fungicide enhancers effective for treating plants infected with fungal pathogens BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-02-04 US disclosed
US-20220039381-A1 FUNGICIDE ENHANCERS EFFECTIVE FOR TREATING PLANTS INFECTED WITH FUNGAL PATHOGENS UNIV TEXAS (US) 2022-02-10 US disclosed
US-20110203990-A1 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME MURPHY ANDREW PATRICK 2011-08-25 US disclosed
US-20110203990-A1 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME MURPHY ANDREW PATRICK 2011-08-25 US disclosed
US-7806275-B2 Chlorine resistant polyamides and membranes made from the same THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE INTERIOR, THE BUREAU OF RECLAMATION (US) 2010-10-05 US disclosed
US-7806275-B2 Chlorine resistant polyamides and membranes made from the same THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE INTERIOR, THE BUREAU OF RECLAMATION (US) 2010-10-05 US disclosed
WO-2008140840-A1 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME GOVERNMENT OF THE USA AS REPRESENTED BY THE DEPARTMENT OF THE INTERIOR - BUREAU OF RECLAMATION (US) 2008-11-20 WO disclosed
US-20080277333-A1 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME SEPARATION SYSTEMS TECHNOLOGY INC. 2008-11-13 US disclosed
US-5807885-A Amidine derivatives with nitric oxide synthetase activities ASTRA AKTIEBOLAG (SE) 1998-09-15 US disclosed
CN-1155278-A Arylthio compounds as antibacteral and antiviral agents WARNER LAMBERT CO (US) 1997-07-23 CN disclosed
EP-0770079-A1 HETEROBICYCLIC DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-05-02 EP disclosed
CN-1132505-A Amidine derivatives with nitric oxide synthetase activities ASTERA CO (SE) 1996-10-02 CN disclosed
EP-0716661-A1 PSEUDO- AND NON-PEPTIDE BRADYKININ RECEPTOR ANTAGONISTS SCIOS NOVA INC. (US) 1996-06-19 EP disclosed
WO-1996001825-A1 HETEROBICYCLIC DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-01-25 WO disclosed
WO-1995007294-A1 PSEUDO- AND NON-PEPTIDE BRADYKININ RECEPTOR ANTAGONISTS SCIOS NOVA INC. (US) 1995-03-16 WO disclosed
WO-1995005363-A1 AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES ASTRA AKTIEBOLAG (SE) 1995-02-23 WO disclosed
US-4499167-A Photoconductive compositions comprising an organic photoconductor and an amide compound and electro-photographic light-sensitive materials using the compositions FUJI PHOTO FILM CO., LTD. (JP) 1985-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12213482-B2 Fungicide enhancers effective for treating plants infected with fungal pathogens APEH, TH, AOC3 MEN1 3015/4885KMT2A 988/4885MAPT 1252/4885
US-20220039381-A1 FUNGICIDE ENHANCERS EFFECTIVE FOR TREATING PLANTS INFECTED WITH FUNGAL PATHOGENS APEH, TH, ENY2 MEN1 2562/4885KMT2A 1314/4885MAPT 1400/4885
US-20110203990-A1 CHLORINE RESISTANT POLYAMIDES AND MEMBRANES MADE FROM THE SAME CLIC1, CLIC4, CLCN2 MEN1 954/4885KMT2A 207/4885MAPT 4427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.