SCHEMBL6796558

SCHEMBL6796558

O=C(O)CN(C(=O)OCC1c2ccccc2-c2ccccc21)C1Cc2ccccc2C1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
FABP5 Q01469 3/20 0.43
FABP7 O15540 2/20 0.43
EPHX2 P34913 1/20 0.39
CASP3 P42574 2/20 0.38
OPRD1 P41143 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11902048 0.89 KMT2A (0.45) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL3173765 0.86 KMT2A (0.44) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL341372 0.85 KMT2A (0.43) KMT2AFABP5FABP7EPHX2OPRD1
SCHEMBL6651104 0.83 KMT2A (0.41) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL2943202 0.82 KMT2A (0.41) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL377928 0.81 KMT2A (0.44) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL15297397 0.80 USP30 (0.41) KMT2AFABP5FABP7
SCHEMBL1869833 0.79 FABP5 (0.50) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL3580338 0.78 GPR119 (0.44) KMT2A
SCHEMBL2355443 0.78 KMT2A (0.49) KMT2AFABP5FABP7EPHX2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260036595-A1 STRUCTURE-BASED PEPTIDES FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES IN PREECLAMPSIA THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-02-05 US disclosed
US-20250362310-A1 STRUCTURE-BASED PROBE FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-11-27 US disclosed
US-20040014676-A1 SRC kinase inhibitors useful for treating osteoporosis ARIAD PHARMACEUTICALS INC. 2004-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014676-A1 SRC kinase inhibitors useful for treating osteoporosis SRC, CTTN, YES1 KMT2A 1865/4885FABP5 2465/4885FABP7 4354/4885
US-20260036595-A1 STRUCTURE-BASED PEPTIDES FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES IN PREECLAMPSIA TTR, APP, SERPINA3 KMT2A 4282/4885FABP5 115/4885FABP7 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.