Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15297397 | 0.90 | USP30 (0.41) | GPR119KMT2AUSP30KDM4EPKM | |
| SCHEMBL31370277 | 0.85 | USP30 (0.47) | GPR119MEN1KMT2AUSP30KDM4E | |
| SCHEMBL11902048 | 0.83 | KMT2A (0.45) | KMT2A | |
| SCHEMBL16094894 | 0.83 | JAK2 (0.49) | GPR119MEN1KMT2AUSP30KDM4E | |
| SCHEMBL23924702 | 0.82 | NAMPT (0.41) | GPR119USP30KDM4EPKMBACE1 | |
| SCHEMBL30267608 | 0.82 | NAMPT (0.41) | GPR119USP30KDM4EPKMBACE1 | |
| SCHEMBL25657529 | 0.81 | KMT2A (0.39) | KMT2A | |
| SCHEMBL3173765 | 0.81 | KMT2A (0.44) | KMT2A | |
| SCHEMBL18926981 | 0.81 | BACE1 (0.51) | GPR119KMT2AKDM4EPKMBACE1 | |
| SCHEMBL31210310 | 0.81 | BACE1 (0.51) | GPR119KMT2AKDM4EPKMBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2026-01-01 | — | — | US | disclosed |
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2025-07-29 | — | — | US | disclosed |
| EP-3303367-B1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2025-06-18 | — | — | EP | disclosed |
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | UNIV NEW YORK (US) | 2024-06-13 | — | — | US | disclosed |
| US-20240124539-A1 | CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME | NEW YORK UNIVERSITY | 2024-04-18 | — | — | US | disclosed |
| US-11891422-B2 | NEMO coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2024-02-06 | — | — | US | disclosed |
| US-20220289802-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | CORNELL UNIVERSITY | 2022-09-15 | — | — | US | disclosed |
| US-11440938-B2 | Stabilized minimal coiled-coil mimetics | NEW YORK UNIVERSITY (US) | 2022-09-13 | — | — | US | disclosed |
| US-20210277059-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2021-09-09 | — | — | US | disclosed |
| US-10851133-B2 | Stabilized minimal coiled-coil mimetics | NEW YORK UNIVERSITY (US) | 2020-12-01 | — | — | US | disclosed |
| US-20180162907-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | NEW YORK UNIVERSITY | 2018-06-14 | — | — | US | disclosed |
| EP-3303367-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | New York University (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016201007-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | NEW YORK UNIVERSITY (US) | 2016-12-15 | — | — | WO | disclosed |
| US-20100048549-A1 | Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 | Wurster, Siegfried (FI) | 2010-02-25 | — | — | US | disclosed |
| US-20080076824-A1 | modified glycinamides: Valine-alphahydroxy-glycinamide | CHRONTECH PHARMA AB (SE) | 2008-03-27 | — | — | US | disclosed |
| US-20080076824-A1 | modified glycinamides: Valine-alphahydroxy-glycinamide | CHRONTECH PHARMA AB (SE) | 2008-03-27 | — | — | US | disclosed |
| US-20080076824-A1 | modified glycinamides: Valine-alphahydroxy-glycinamide | CHRONTECH PHARMA AB (SE) | 2008-03-27 | — | — | US | disclosed |
| US-20040082079-A1 | Low affinity screening method | GRAFFINITY PHARMACEUTICALS AG. (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1360489-A1 | LOW AFFINITY SCREENING METHOD | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002063299-A1 | LOW AFFINITY SCREENING METHOD | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | GPR119 2223/4885MEN1 200/4885KMT2A 4091/4885 |
| US-20080076824-A1 | modified glycinamides: Valine-alphahydroxy-glycinamide | GALE, ENGASE, UGGT1 | GPR119 953/4885MEN1 3483/4885KMT2A 1219/4885 |
| US-11440938-B2 | Stabilized minimal coiled-coil mimetics | COIL, CALCOCO2, SMC2 | GPR119 1525/4885MEN1 130/4885KMT2A 2874/4885 |
| US-10851133-B2 | Stabilized minimal coiled-coil mimetics | COIL, CALCOCO2, CRYZ | GPR119 2015/4885MEN1 220/4885KMT2A 3783/4885 |
| US-20210277059-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | COIL, CALCOCO2, CRYZ | GPR119 2015/4885MEN1 220/4885KMT2A 3783/4885 |
| US-20100048549-A1 | Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 | SSTR1, SSTR4, SSTR3 | GPR119 21/4885MEN1 488/4885KMT2A 2996/4885 |
| US-20240124539-A1 | CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME | SOS2, SOS1, F2 | GPR119 3453/4885MEN1 452/4885KMT2A 4401/4885 |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | DDX21, PHAX, RBX1 | GPR119 2061/4885MEN1 2283/4885KMT2A 2849/4885 |
| US-11891422-B2 | NEMO coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | GPR119 2223/4885MEN1 200/4885KMT2A 4091/4885 |
| US-20220289802-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | GPR119 2223/4885MEN1 200/4885KMT2A 4091/4885 |
| US-20180162907-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | COIL, CALCOCO2, CRYZ | GPR119 2015/4885MEN1 220/4885KMT2A 3783/4885 |
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | GPR119 2341/4885MEN1 144/4885KMT2A 3979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.