SCHEMBL6796765

SCHEMBL6796765

N#Cc1ccc(N(C(=O)c2ccc(O)cc2)n2cnnc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8446590 0.94 CYP19A1 (0.48) CYP19A1
SCHEMBL6799562 0.80 CYP19A1 (0.63) CYP19A1
SCHEMBL2112966 0.77 CA2 (0.55) CYP19A1
SCHEMBL6794239 0.75 CA2 (0.52)
SCHEMBL2113091 0.72 ESR1 (0.56)
SCHEMBL3233064 0.72 CYP19A1 (1.00) CYP19A1
SCHEMBL3236162 0.72 CYP19A1 (0.56) CYP19A1
SCHEMBL6799435 0.70 MEN1 (0.72) CYP19A1
SCHEMBL3231294 0.70 CYP19A1 (1.00) CYP19A1
SCHEMBL8443364 0.70 CYP19A1 (0.53) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1308297-C Phenyl sulfamate derivs. TEIKOKU HORMONE MFG CO LTD (JP) 2007-04-04 CN disclosed
US-6762205-B1 STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION TEIKOKU HORMONE MFG. CO., LTD. (JP) 2004-07-13 US disclosed
CN-1360570-A Phenyl sulfamate derivs. TEIKOKU HORMONE MFG CO LTD (JP) 2002-07-24 CN disclosed
EP-1193250-A1 PHENYL SULFAMATE DERIVATIVES Teikoku Hormone Mfg. Co., Ltd. (JP) 2002-04-03 EP disclosed