Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | PDK1 | Q15118 | 7/20 | 0.67 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.67 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.67 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802291 | 0.93 | MEN1 (0.76) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL6798512 | 0.86 | MEN1 (0.55) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL6799801 | 0.84 | GAA (0.62) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL27565502 | 0.81 | MEN1 (0.74) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL6796753 | 0.81 | NSD2 (0.77) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL6800779 | 0.81 | MEN1 (0.55) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL6795598 | 0.80 | MEN1 (0.60) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL2112966 | 0.79 | CA2 (0.55) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL6797228 | 0.77 | ESR1 (0.61) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL6794239 | 0.76 | CA2 (0.52) | MEN1NPC1KMT2APDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |