SCHEMBL6796850

SCHEMBL6796850

COc1ccc(CCNC(=O)/C(=C\OC(F)F)c2ccc(C)cc2)cc1OC

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
THRB P10828 1/20 0.60
MAPT P10636 3/20 0.58
LMNA P02545 3/20 0.54
KMT2A Q03164 1/20 0.52
ADRB2 P07550 1/20 0.52
ADRB1 P08588 1/20 0.52
ADRB3 P13945 1/20 0.52
GAA P10253 1/20 0.51
PKM P14618 1/20 0.51
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6796855 1.00 ALDH1A1 (0.62) ALDH1A1THRBMAPTLMNAKMT2A
SCHEMBL6796731 0.94 ALDH1A1 (0.54) ALDH1A1THRBMAPTLMNAKMT2A
SCHEMBL6796728 0.94 ALDH1A1 (0.54) ALDH1A1THRBMAPTLMNAKMT2A
SCHEMBL6797880 0.92 ALDH1A1 (0.52) ALDH1A1THRBMAPTLMNAKMT2A
SCHEMBL6797885 0.92 ALDH1A1 (0.52) ALDH1A1THRBMAPTLMNAKMT2A
SCHEMBL6801546 0.92 MAPT (0.58) ALDH1A1MAPTLMNAKMT2AGAA
SCHEMBL6801543 0.92 MAPT (0.58) ALDH1A1MAPTLMNAKMT2AGAA
SCHEMBL6802677 0.91 GAA (0.64) ALDH1A1THRBMAPTLMNAGAA
SCHEMBL6801944 0.91 ALDH1A1 (0.58) ALDH1A1THRBMAPTGAACA12
SCHEMBL6802680 0.91 GAA (0.64) ALDH1A1THRBMAPTLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6762321-B2 SUCH AS N-(2-(3,4-DIMETHOXYPHENYL)ETHYL)-3-DIFLUOROMETHOXY-2-(4 -METHYLPHENYL)ACRYLAMIDE; FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-07-13 US disclosed
US-20030195354-A1 Amide compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-16 US disclosed
EP-1295868-A1 AMIDE COMPOUNDS AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195354-A1 Amide compounds and use thereof CBR1, CBR3, NAT1 ALDH1A1 244/4885THRB 3020/4885MAPT 3676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.