Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 14/20 | 0.51 |
| ▸ | DOCK5 | Q9H7D0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20936951 | 0.86 | DPP4 (0.57) | DPP4DPP8FAAHDOCK5 | |
| SCHEMBL18780582 | 0.83 | DPP4 (0.59) | DPP4DPP8FAAHDOCK5 | |
| SCHEMBL15084324 | 0.81 | DPP4 (0.54) | DPP4DPP8FAAHDOCK5 | |
| SCHEMBL6793565 | 0.80 | KMT2A (0.55) | FAAH | |
| SCHEMBL27267535 | 0.77 | FAAH (0.58) | DPP4DPP8FAAH | |
| SCHEMBL3115573 | 0.75 | FUCA1 (0.55) | — | |
| SCHEMBL18780577 | 0.75 | FAAH (0.57) | DPP4DPP8FAAH | |
| SCHEMBL3595508 | 0.74 | FAAH (0.56) | DPP4DPP8FAAH | |
| SCHEMBL807181 | 0.74 | DPP4 (0.47) | DPP4DPP8FAAHDOCK5 | |
| SCHEMBL6797735 | 0.72 | FAAH (0.49) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821964-B2 | FOR PROPHYLAXIS AND THERAPY OF DISEASES ASSOCIATED WITH MONOCYTE ACCUMULATION, LYMPHOCYTE ACCUMULATION OR LEUCOCYTE ACCUMULATION | PFIZER INC | 2004-11-23 | — | — | US | disclosed |