SCHEMBL679743

SCHEMBL679743

CC(=CCCc1cccc(C)c1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 1/20 0.49
CTBP2 P56545 1/20 0.48
TAAR1 Q96RJ0 1/20 0.46
GPR84 Q9NQS5 1/20 0.43
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
MAOB P27338 2/20 0.41
DAO P14920 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
GRM2 Q14416 1/20 0.41
GRM3 Q14832 1/20 0.41
AKR1C3 P42330 1/20 0.41
NR3C2 P08235 1/20 0.41
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12003262 1.00 GPR52 (0.49) GPR52CTBP2TAAR1GPR84KDM4E
SCHEMBL1137523 0.84 CHRM2 (0.47) CTBP2TAAR1
SCHEMBL19656182 0.84 TAAR1 (0.46) TAAR1THRATHRBFFAR4MAOB
SCHEMBL1137527 0.84 CHRM2 (0.47) CTBP2TAAR1
SCHEMBL5487172 0.84 CTBP2 (0.50) GPR52CTBP2TAAR1KDM4EALDH1A1
SCHEMBL197321 0.83 GRIK1 (0.53) GPR52ALDH1A1NPC1RAB9AAKR1C3
SCHEMBL197322 0.83 GRIK1 (0.53) GPR52ALDH1A1NPC1RAB9AAKR1C3
SCHEMBL445494 0.83 GPR52 (0.49) GPR52GPR84FFAR4
SCHEMBL440626 0.83 TAAR1 (0.48) CTBP2TAAR1ALDH1A1MAOB
SCHEMBL1921015 0.83 GPR52 (0.49) GPR52GPR84FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 EP claimed
EP-2341102-B1 Thermoplastic resin composition revealing improved impact strength and melt flow property CHEIL IND INC (KR) 2015-12-02 EP claimed
US-8907013-B2 Polycarbonate resin composition and molded product using the same CHEIL INDUSTRIES INC. (KR) 2014-12-09 US claimed
US-8835558-B2 Polylactic acid/polycarbonate resin composition and molded product made using the same CHEIL INDUSTRIES INC. (KR) 2014-09-16 US claimed
EP-2582409-B1 HIGH REFRACTIVE INDEX, ACRYLIC OPHTHALMIC DEVICE MATERIALS WITH REDUCED GLISTENINGS NOVARTIS AG (CH) 2014-09-10 EP claimed
EP-2199342-B1 Polylactic acid/polycarbonate resin composition and molded product made using the same CHEIL IND INC (KR) 2014-07-30 EP claimed
US-8735490-B2 Thermoplastic resin composition having improved impact strength and melt flow properties CHEIL INDUSTRIES INC. (KR) 2014-05-27 US claimed
EP-2268709-B1 SCRATCH RESISTANT THERMOPLASTIC RESIN COMPOSITION CHEIL IND INC (KR) 2013-10-02 EP claimed
EP-2204412-B1 Polycarbonate resin composition with improved scratch resistance and melt flow index CHEIL IND INC (KR) 2012-08-29 EP claimed
US-20110281995-A1 Polycarbonate Resin Composition and Molded Product Using the Same CHEIL INDUSTRIES INC. (KR) 2011-11-17 US claimed
EP-2341102-A1 Thermoplastic resin composition revealing improved impact strength and melt flow property Cheil Industries Inc. (KR) 2011-07-06 EP claimed
US-20110160377-A1 Thermoplastic Resin Composition Having Improved Impact Strength and Melt Flow Properties CHEIL INDUSTRIES INC. (KR) 2011-06-30 US claimed
US-20100160559-A1 Polylactic Acid/Polycarbonate Resin Composition and Molded Product Made Using the Same CHEIL INDUSTRIES INC. (KR) 2010-06-24 US claimed
EP-2199342-A2 Polylactic acid/polycarbonate resin composition and molded product made using the same Cheil Industries Inc. (KR) 2010-06-23 EP claimed
EP-1080382-B1 HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS ALCON INC (CH) 2009-07-08 EP claimed
US-11649401-B2 Quantum dot-containing material, method of preparing the same, and optical member and apparatus including the quantum dot-containing material SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-20230006135-A1 COMPOSITION FOR ENCAPSULATING ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DIODE DISPLAY COMPRISING ORGANIC LAYER FORMED USING THE SAME SAMSUNG SDI CO., LTD. (KR) 2023-01-05 US disclosed
EP-2184321-A2 Thermoplastic resin composition and molded product made using the same Cheil Industries Inc. (KR) 2010-05-12 EP disclosed
US-20100113697-A1 Thermoplastic Resin Composition and Molded Product Made Using the Same CHEIL INDUSTRIES INC. 2010-05-06 US disclosed