SCHEMBL679746

SCHEMBL679746

CCCSCc1cnc(C)o1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.38
ACHE P22303 9/20 0.33
BCHE P06276 8/20 0.33
APEX1 P27695 1/20 0.33
PRMT6 Q96LA8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL679623 0.76
SCHEMBL5535219 0.74
SCHEMBL2629342 0.73
SCHEMBL12255168 0.70 CCNB2 (0.36) TYRACHEAPEX1
SCHEMBL5538019 0.69 TDP1 (0.35)
SCHEMBL25626148 0.68
SCHEMBL5536581 0.68 MAPT (0.37)
SCHEMBL5833261 0.67
SCHEMBL22792609 0.67
SCHEMBL15229474 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8841328-B2 Selective insecticides based on anthranilic acid diamides and safeners BAYER CROPSCIENCE AG (DE) 2014-09-23 US disclosed
US-8841328-B2 Selective insecticides based on anthranilic acid diamides and safeners BAYER CROPSCIENCE AG (DE) 2014-09-23 US disclosed
US-20140087946-A1 Selective Insecticides Based on Anthranilic Acid Diamides and Safeners BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-03-27 US disclosed
US-20140087946-A1 Selective Insecticides Based on Anthranilic Acid Diamides and Safeners BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-03-27 US disclosed
US-8017632-B2 for controlling insects and/or arachnids BAYER CROPSCIENCE AG (DE) 2011-09-13 US disclosed
US-8017632-B2 for controlling insects and/or arachnids BAYER CROPSCIENCE AG (DE) 2011-09-13 US disclosed
US-20110059991-A1 Selective Insecticides Based on Anthranilic Acid Diamides and Safeners BAYER CROPSCIENCE AG (DE) 2011-03-10 US disclosed
US-20110059991-A1 Selective Insecticides Based on Anthranilic Acid Diamides and Safeners BAYER CROPSCIENCE AG (DE) 2011-03-10 US disclosed
US-20080221167-A1 for controlling insects and/or arachnids BAYER CROPSCIENCE AG (DE) 2008-09-11 US disclosed
US-20080221167-A1 for controlling insects and/or arachnids BAYER CROPSCIENCE AG (DE) 2008-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140087946-A1 Selective Insecticides Based on Anthranilic Acid Diamides and Safeners DDC, DDT, AADAC TYR 1084/4885ACHE 1071/4885BCHE 3074/4885
US-20110059991-A1 Selective Insecticides Based on Anthranilic Acid Diamides and Safeners DDC, DDT, AADAC TYR 1084/4885ACHE 1071/4885BCHE 3074/4885
US-20080221167-A1 for controlling insects and/or arachnids CRYAB, DDC, DDT TYR 580/4885ACHE 387/4885BCHE 1989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.