Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843102 | 0.72 | CRHR1 (0.69) | CRHR1 | |
| SCHEMBL6804399 | 0.71 | CRHR1 (0.54) | CRHR1LMNA | |
| SCHEMBL16606728 | 0.70 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL6094145 | 0.69 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL30397878 | 0.69 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL123421 | 0.69 | CRHR1 (1.00) | CRHR1 | |
| Hydrochloric Acid SCHEMBL3103253 | 0.68 | CRHR1 (0.97) | CRHR1 | |
| SCHEMBL5843759 | 0.68 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL8202290 | 0.68 | CRHR1 (0.69) | CRHR1 | |
| SCHEMBL1030532 | 0.68 | CRHR1 (0.62) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833378-B2 | Pyridines, pyrimidines, purinones, pyrrolopyrimidinones and pyrrolopyridinones; useful in the treatment disorders including CNS and stress-related disorders. | PFIZER INC | 2004-12-21 | — | — | US | disclosed |
| EP-1263732-A1 | CORTICOTROPIN RELEASING FACTOR ANTAGONISTS | Pfizer Products Inc. (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001053263-A1 | CORTICOTROPIN RELEASING FACTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2001-07-26 | — | — | WO | disclosed |