Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30397878 | 0.82 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL123421 | 0.82 | CRHR1 (1.00) | CRHR1 | |
| Hydrochloric Acid SCHEMBL3103253 | 0.81 | CRHR1 (0.97) | CRHR1 | |
| SCHEMBL29482253 | 0.80 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL3226278 | 0.80 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL5843102 | 0.80 | CRHR1 (0.69) | CRHR1 | |
| Hydrochloric Acid SCHEMBL3103251 | 0.80 | CRHR1 (0.95) | CRHR1 | |
| SCHEMBL5844686 | 0.78 | CRHR1 (0.86) | CRHR1 | |
| SCHEMBL5843725 | 0.77 | CRHR1 (0.72) | CRHR1 | |
| SCHEMBL5844562 | 0.77 | CRHR1 (0.72) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043260-A | Method of treating heart failure | PFIZER INC (US) | 2000-03-28 | — | — | US | claimed |
| EP-0951906-A1 | Use of 3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-pyridines for treating heart failure | Pfizer Products Inc. (US) | 1999-10-27 | — | — | EP | claimed |
| US-6043260-A | Method of treating heart failure | PFIZER INC (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0951906-A1 | Use of 3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-pyridines for treating heart failure | Pfizer Products Inc. (US) | 1999-10-27 | — | — | EP | disclosed |