Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437156 | 0.90 | CA12 (0.38) | CA12CA1CA9 | |
| SCHEMBL6437883 | 0.82 | CNR2 (0.31) | — | |
| SCHEMBL5360953 | 0.77 | CA12 (0.44) | CA12CA1CA9 | |
| SCHEMBL6437495 | 0.77 | CA12 (0.38) | CA12CA1CA9 | |
| SCHEMBL6434922 | 0.74 | CA12 (0.36) | CA12CA1CA9 | |
| SCHEMBL6804163 | 0.74 | CA12 (0.40) | CA12CA1CA9 | |
| SCHEMBL18244963 | 0.73 | ESR2 (0.47) | CA12CA1CA9 | |
| SCHEMBL6433944 | 0.73 | CA12 (0.39) | CA12CA1CA9 | |
| SCHEMBL5363897 | 0.73 | CA12 (0.39) | CA12CA1CA9 | |
| SCHEMBL5360778 | 0.73 | CA12 (0.39) | CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828460-B2 | Containing at least one ester, oxime, sulfonamide, hydroxyamino or alkyoxyamino functionality; skin lightening agents; tyrosinase inhibitors | PFIZER INC. | 2004-12-07 | — | — | US | disclosed |
| US-20020161041-A1 | Resorcinol derivatives | PFIZER INC. | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161041-A1 | Resorcinol derivatives | NQO1, LRAT, ALDH1A2 | CA12 4452/4885CA1 4863/4885CA9 3517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.