Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | HMGCR | P04035 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27698390 | 0.86 | CYP3A4 (0.47) | CYP3A4KMT2APAX8HMGCRMEN1 | |
| SCHEMBL27667006 | 0.86 | HMGCR (0.56) | CYP3A4KMT2APAX8HMGCRMEN1 | |
| SCHEMBL7460397 | 0.85 | CYP3A4 (0.59) | CYP3A4KMT2APAX8HMGCRMEN1 | |
| SCHEMBL10556328 | 0.85 | SMN1; SMN2 (0.46) | CYP3A4KMT2AHMGCRKDM4EALDH1A1 | |
| SCHEMBL28611973 | 0.85 | CYP3A4 (0.46) | CYP3A4KMT2APAX8HMGCRMEN1 | |
| SCHEMBL11321060 | 0.84 | HMGCR (0.49) | CYP3A4KMT2APAX8HMGCRMEN1 | |
| SCHEMBL4764754 | 0.83 | HMGCR (0.72) | CYP3A4KMT2APAX8HMGCRMEN1 | |
| SCHEMBL15677777 | 0.82 | HMGCR (0.47) | CYP3A4KMT2APAX8HMGCRMEN1 | |
| SCHEMBL10497736 | 0.82 | CYP3A4 (0.55) | CYP3A4KMT2APAX8HMGCRMEN1 | |
| SCHEMBL8544834 | 0.82 | CYP3A4 (0.55) | CYP3A4KMT2APAX8HMGCRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311472-B1 | COGNITIVE DISORDER-AMELIORATING AGENT | JAPAN ROYAL JELLY CO LTD (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-20130129832-A1 | COGNITIVE IMPAIRMENT AMELIORANT | TOHOKU UNIVERSITY (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20110287106-A1 | COGNITIVE IMPAIRMENT AMELIORANT | JAPAN ROYAL JELLEY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
| EP-2311472-A1 | COGNITIVE DISORDER-AMELIORATING AGENT | Japan Royal Jelly Co., Ltd. (JP) | 2011-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129832-A1 | COGNITIVE IMPAIRMENT AMELIORANT | CHAT, ACHE, PSEN1 | CYP3A4 4098/4885KMT2A 768/4885PAX8 2971/4885 |
| US-20110287106-A1 | COGNITIVE IMPAIRMENT AMELIORANT | CHAT, ACHE, PSEN1 | CYP3A4 4098/4885KMT2A 768/4885PAX8 2971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.