SCHEMBL6798771

SCHEMBL6798771

CCCCCCCCCN(c1c(F)c(F)c(F)c(F)c1F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.37
MGLL Q99685 1/20 0.32
TSHR P16473 1/20 0.31
THRB P10828 1/20 0.31
FAAH O00519 7/20 0.31
CES1 P23141 5/20 0.31
CES2 O00748 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6785902 1.00 DNM1 (0.37) DNM1MGLLTSHRTHRBFAAH
SCHEMBL6791280 0.85 DNM1 (0.34) DNM1MGLL
SCHEMBL6790821 0.81 DNM1 (0.31) DNM1
SCHEMBL6792866 0.79
SCHEMBL6794675 0.77
SCHEMBL6790673 0.76 ALDH1A1 (0.35) TSHRCA2
SCHEMBL5715545 0.76 DNM1 (0.39) DNM1MGLLTSHRTHRBCA12
SCHEMBL5716286 0.76 DNM1 (0.39) DNM1MGLLTSHRTHRBCA12
SCHEMBL21519592 0.75 DNM1 (0.42) DNM1MGLLTSHRTHRBCA12
SCHEMBL5716072 0.75 DNM1 (0.42) DNM1MGLLTSHRTHRBCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed