Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | HTR2B | P41595 | 4/20 | 0.50 |
| ▸ | APOB | P04114 | 3/20 | 0.50 |
| ▸ | MTTP | P55157 | 3/20 | 0.50 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.42 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804070 | 0.93 | MEN1 (0.46) | HTR2CHTR2BAPOBMTTPEIF2AK3 | |
| SCHEMBL6798908 | 0.93 | HTR2C (0.45) | HTR2CHTR2BAPOBMTTPEIF2AK3 | |
| SCHEMBL6801440 | 0.91 | MTTP (0.52) | HTR2CHTR2BAPOBMTTPMEN1 | |
| SCHEMBL6668494 | 0.90 | MTTP (0.51) | HTR2CHTR2BAPOBMTTPEIF2AK3 | |
| SCHEMBL6670698 | 0.89 | HTR2C (0.48) | HTR2CHTR2BEIF2AK3MEN1KMT2A | |
| SCHEMBL6644163 | 0.88 | MEN1 (0.54) | HTR2CHTR2BEIF2AK3MEN1KMT2A | |
| SCHEMBL6924881 | 0.87 | MAPT (0.55) | HTR2CHTR2BEIF2AK3MEN1KMT2A | |
| SCHEMBL6804744 | 0.86 | HTR2C (0.46) | HTR2CHTR2BAPOBMTTPEIF2AK3 | |
| SCHEMBL6804640 | 0.86 | SMO (0.50) | HTR2CHTR2BEIF2AK3HTR2AMAPT | |
| SCHEMBL6808797 | 0.86 | MTTP (0.49) | HTR2CHTR2BAPOBMTTPEIF2AK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | HTR2C 2433/4885HTR2B 928/4885APOB 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.