Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | STAT6 | P42226 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9186785 | 0.90 | CYP1A2 (0.71) | CYP1A2CYP2D6SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL6141647 | 0.85 | CYP1A2 (0.83) | CYP1A2CYP2D6SMN1; SMN2ALDH1A1MAPK1 | |
| Bromide SCHEMBL5084016 | 0.84 | CYP1A2 (0.80) | CYP1A2CYP2D6SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL10535954 | 0.83 | SMN1; SMN2 (0.82) | CYP1A2CYP2D6SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL14155879 | 0.82 | SMN1; SMN2 (0.80) | CYP1A2CYP2D6SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL13164429 | 0.82 | SMN1; SMN2 (0.80) | CYP1A2CYP2D6SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7401382 | 0.81 | CYP1A2 (0.71) | CYP1A2CYP2D6SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL28621136 | 0.81 | CYP1A2 (0.75) | CYP1A2CYP2D6SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL5837665 | 0.80 | CYP1A2 (1.00) | CYP1A2CYP2D6SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL20545556 | 0.79 | LMNA (0.67) | SMN1; SMN2ALDH1A1MAPK1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710045-B2 | FOR CONTROLLING ANIMAL PESTS, IN PARTICULAR INSECTS, ARACHNIDS AND NEMATODES | BAYER CROPSCIENCE AG (DE) | 2004-03-23 | — | — | US | disclosed |
| US-20030187259-A1 | Heterocylic fluoroalkenyl thioethers and the use thereof as pesticides (IV) | BAYER CROPSCIENCE AG (DE) | 2003-10-02 | — | — | US | disclosed |
| EP-1311497-A1 | HETEROCYCLIC FLUOROALKENYL THIOETHERS AND THE USE THEREOF AS PESTICIDES (IV) | Bayer CropScience AG (DE) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002006259-A1 | HETEROCYCLIC FLUOROALKENYL THIOETHERS AND THE USE THEREOF AS PESTICIDES (IV) | BAYER CROPSCIENCE AG (DE) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187259-A1 | Heterocylic fluoroalkenyl thioethers and the use thereof as pesticides (IV) | DDT, CYP4F2, CYP4F3 | CYP1A2 25/4885CYP2D6 106/4885SMN1; SMN2 3173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.