SCHEMBL6799425

SCHEMBL6799425

CC(=O)Nc1cccc(COc2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cn2)n1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MTTP P55157 8/20 0.49
APOB P04114 7/20 0.49
SMO Q99835 1/20 0.47
HTR2C P28335 3/20 0.43
HTR2A P28223 2/20 0.43
HTR2B P41595 2/20 0.43
UGCG Q16739 1/20 0.43
GAA P10253 1/20 0.42
KIT P10721 1/20 0.42
KDR P35968 1/20 0.42
MAPK14 Q16539 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6793010 0.89 HTR2C (0.50) MTTPAPOBSMOHTR2CHTR2A
SCHEMBL6795248 0.87 SMO (0.47) MTTPAPOBSMOHTR2CHTR2A
SCHEMBL6796059 0.85 SMO (0.58) MTTPAPOBSMOHTR2CHTR2A
SCHEMBL6788348 0.83 MTTP (0.51) MTTPAPOBSMOUGCG
SCHEMBL6793979 0.83 MTTP (0.53) MTTPAPOBSMOUGCG
SCHEMBL6792606 0.81 MTTP (0.49) MTTPAPOBSMOUGCG
SCHEMBL6793643 0.80 MTTP (0.51) MTTPAPOBSMOUGCG
SCHEMBL6805247 0.79 MTTP (0.49) MTTPAPOBSMOGAA
SCHEMBL6497723 0.79 APOB (0.46) MTTPAPOBSMOHTR2CHTR2A
SCHEMBL6788361 0.78 SMO (0.56) MTTPAPOBSMOHTR2CHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 MTTP 363/4885APOB 1/4885SMO 2094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.