Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.48 |
| ▸ | MTTP | P55157 | 12/20 | 0.41 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806278 | 0.92 | SMO (0.47) | SMOMTTPSRPK1TRPV1 | |
| SCHEMBL6669064 | 0.90 | SRPK1 (0.45) | SMOSRPK1 | |
| SCHEMBL6803527 | 0.83 | SMO (0.47) | SMOMTTPSRPK1 | |
| SCHEMBL6804688 | 0.83 | SMO (0.61) | SMOMTTP | |
| SCHEMBL6667845 | 0.83 | SRPK1 (0.44) | SMOSRPK1 | |
| SCHEMBL6809779 | 0.78 | SMO (0.55) | SMOMTTPLMNA | |
| SCHEMBL6805171 | 0.77 | SMO (0.52) | SMOMTTPLMNAHTT | |
| SCHEMBL6801953 | 0.76 | SMO (0.52) | SMOMTTPLMNA | |
| SCHEMBL6804697 | 0.75 | SMO (0.54) | SMOMTTP | |
| SCHEMBL6803858 | 0.75 | SMO (0.52) | SMOMTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | SMO 4390/4885MTTP 108/4885SRPK1 4150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.