Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRPK1 | Q96SB4 | 13/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667845 | 0.92 | SRPK1 (0.44) | SRPK1SORT1ALDH1A1HTR2AHTR2C | |
| SCHEMBL6799432 | 0.90 | SMO (0.48) | SRPK1SMO | |
| SCHEMBL6667054 | 0.85 | SORT1 (0.40) | SRPK1SORT1HTR2AHTR2CHTR2B | |
| SCHEMBL6664848 | 0.84 | HTR2A (0.53) | SRPK1SORT1HTR2AHTR2CHTR2B | |
| SCHEMBL6663338 | 0.84 | HTR2A (0.53) | SORT1HTR2AHTR2CHTR2BSMO | |
| SCHEMBL6806278 | 0.82 | SMO (0.47) | SRPK1NTRK1SMO | |
| SCHEMBL6803527 | 0.76 | SMO (0.47) | SRPK1HTR2AHTR2CHTR2BSMO | |
| SCHEMBL6805171 | 0.76 | SMO (0.52) | ALDH1A1HTR2AHTR2CHTR2BNTRK1 | |
| SCHEMBL6664745 | 0.76 | EIF2AK3 (0.46) | HTR2AHTR2CHTR2BSMO | |
| SCHEMBL6635095 | 0.75 | PARP1 (0.48) | SRPK1SORT1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |