SCHEMBL6799552

SCHEMBL6799552

CNC(=O)C(Cc1ccc([N+](=O)[O-])cc1)NS(=O)(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 10/20 0.55
MMP9 P14780 8/20 0.55
ADAMTS4 O75173 1/20 0.52
ITGB3 P05106 1/20 0.51
ITGAV P06756 1/20 0.51
ALDH1A1 P00352 2/20 0.50
MAPT P10636 1/20 0.50
CA2 P00918 2/20 0.48
CTSL P07711 1/20 0.48
CTSB P07858 1/20 0.48
CTSS P25774 1/20 0.48
CTSK P43235 1/20 0.48
MMP1 P03956 2/20 0.48
MMP3 P08254 1/20 0.48
MMP7 P09237 1/20 0.48
MMP13 P45452 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CA12 O43570 1/20 0.48
CA9 Q16790 1/20 0.48
MMP8 P22894 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6799543 1.00 MMP2 (0.55) MMP2MMP9ADAMTS4ITGB3ITGAV
SCHEMBL6802333 0.91 TDP1 (0.56) MMP2MMP9ALDH1A1MAPTCA2
SCHEMBL6802343 0.91 TDP1 (0.56) MMP2MMP9ALDH1A1MAPTCA2
SCHEMBL6912842 0.88 POLB (0.56) MMP2MMP9ALDH1A1MAPTMMP1
SCHEMBL6912827 0.88 POLB (0.56) MMP2MMP9ALDH1A1MAPTMMP1
SCHEMBL28243959 0.86 POLB (0.55) MMP2MMP9ADAMTS4ALDH1A1MAPT
SCHEMBL8919459 0.85 MMP2 (0.63) MMP2MMP9ADAMTS4ITGB3ITGAV
SCHEMBL5189459 0.84 MMP2 (0.73) MMP2MMP9ADAMTS4ALDH1A1MAPT
SCHEMBL26616349 0.84 MMP2 (0.73) MMP2MMP9ADAMTS4ALDH1A1MAPT
SCHEMBL26616346 0.84 MMP2 (0.73) MMP2MMP9ADAMTS4ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074238-A1 PHENETHYLAMINO SULFAMIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO disclosed
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167183-A1 Phenethylamino sulfamic acids PTPRM, PTPRS, PTPRE MMP2 630/4885MMP9 2969/4885ADAMTS4 2158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.