Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.65 |
| ▸ | CTSS | P25774 | 2/20 | 0.65 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSH | P09668 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.41 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025954 | 1.00 | CTSK (0.65) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL9106410 | 1.00 | CTSK (0.65) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL7409458 | 0.93 | CTSK (0.63) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL14152817 | 0.93 | CTSK (0.63) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL2627403 | 0.93 | CTSK (0.63) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL7355314 | 0.90 | CTSK (0.67) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL482062 | 0.87 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL21427213 | 0.87 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL21427220 | 0.87 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 | |
| SCHEMBL8283416 | 0.87 | CTSK (0.70) | CTSKCTSSAAK1HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6797700-B2 | ANTICOAGULANTS | AVENTIS PHARMACEUTICALS, INC. | 2004-09-28 | — | — | US | disclosed |
| US-20020002268-A1 | Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides | AVENTIS PHARMACEUTICALS INC. | 2002-01-03 | — | — | US | disclosed |
| US-6274705-B1 | INHIBIT PLATELET AGGREGATION AND THROMBUS FORMATION, USEFUL IN PREVENTION AND TREATMENT OF THROMBOSIS | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2001-08-14 | — | — | US | disclosed |
| EP-0812205-A4 | ANTITHROMBOTIC AZACYCLOALKYLALKANOYL PEPTIDES AND PSEUDOPEPTIDES | RHONE POULENC RORER PHARMA (US) | 1999-03-31 | — | — | EP | disclosed |
| US-5866685-A | Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1999-02-02 | — | — | US | disclosed |
| EP-0812205-A1 | ANTITHROMBOTIC AZACYCLOALKYLALKANOYL PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1997-12-17 | — | — | EP | disclosed |
| CN-1135717-A | Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides | RHONE POULENC RORER PHARMA (US) | 1996-11-13 | — | — | CN | disclosed |
| WO-1995010295-A1 | ANTITHROMBOTIC AZACYCLOALKYLALKANOYL PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1995-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002268-A1 | Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides | PLAT, SELP, PIGS | CTSK 237/4885CTSS 1480/4885AAK1 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.