SCHEMBL679972

SCHEMBL679972

Nc1cc(N)cc(COC(=O)/C=C/c2ccc(OC(=O)c3ccc(OCCCC(F)(F)C(F)(F)C(F)(F)F)cc3)cc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CA12 O43570 2/20 0.37
CA4 P22748 2/20 0.37
CA6 P23280 2/20 0.37
CA5A P35218 2/20 0.37
CA7 P43166 2/20 0.37
CA9 Q16790 2/20 0.37
CA14 Q9ULX7 2/20 0.37
CA5B Q9Y2D0 2/20 0.37
CA1 P00915 1/20 0.37
MET P08581 3/20 0.37
ABCG2 Q9UNQ0 2/20 0.37
CYP1A1 P04798 1/20 0.37
CYP1B1 Q16678 1/20 0.37
SAE1 Q9UBE0 1/20 0.36
UBA2 Q9UBT2 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678505 0.95 MAPT (0.40) MAPTKDM4ECA12CA4CA6
SCHEMBL2142087 0.93 CA12 (0.37) MAPTKDM4ECA12CA4CA6
SCHEMBL5069444 0.93 CA12 (0.37) MAPTKDM4ECA12CA4CA6
SCHEMBL2139308 0.91 CA12 (0.38) MAPTKDM4ECA12CA4CA6
SCHEMBL679940 0.91 ABCG2 (0.41) MAPTKDM4ECA12CA4CA6
SCHEMBL2136385 0.89 CA12 (0.43) MAPTKDM4ECA12CA4CA6
SCHEMBL1656998 0.89 MAPT (0.37) MAPTKDM4ECA12CA4CA6
SCHEMBL2141657 0.89 CA12 (0.43) MAPTKDM4ECA12CA4CA6
SCHEMBL1563300 0.88 CA12 (0.41) MAPTKDM4ECA12CA4CA6
SCHEMBL28664683 0.88 MAPT (0.38) MAPTKDM4ECA12CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107438653-B Photoalignment composition 罗利克有限公司 2022-01-07 CN disclosed
CN-113652167-A Photoalignment composition 罗利克有限公司 2021-11-16 CN disclosed
US-11053354-B2 Liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2021-07-06 US disclosed
US-20170362381-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2017-12-21 US disclosed
US-20170362381-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2017-12-21 US disclosed
US-9684207-B2 Polymer for alignment films, and liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2017-06-20 US disclosed
US-9684207-B2 Polymer for alignment films, and liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2017-06-20 US disclosed
US-9541797-B2 Liquid crystal display device and method for producing same UNIFIED INNOVATIVE TECHNOLOGY, LLC (US) 2017-01-10 US disclosed
US-9541797-B2 Liquid crystal display device and method for producing same UNIFIED INNOVATIVE TECHNOLOGY, LLC (US) 2017-01-10 US disclosed
EP-1966119-B1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2016-10-19 EP disclosed
EP-2305632-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-06 EP disclosed
EP-2305631-A1 Photocrosslinkable materials Rolic AG (CH) 2011-04-06 EP disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 WO disclosed
EP-1860094-A1 Photocrosslinkable materials Rolic AG (CH) 2007-11-28 EP disclosed
WO-2007071091-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2007-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD MAPT 295/4885KDM4E 1831/4885CA12 1753/4885
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS PARG, PARN, PUF60 MAPT 159/4885KDM4E 2018/4885CA12 744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.