SCHEMBL679980

SCHEMBL679980

Cc1ccc2c3ccc(C)cc3n(Cc3ccccc3)c2c1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.60
MIF P14174 3/20 0.56
CD74 P04233 1/20 0.56
SRC P12931 1/20 0.56
KMT2A Q03164 2/20 0.52
LMNA P02545 1/20 0.52
P2RX4 Q99571 2/20 0.51
C5AR1 P21730 1/20 0.50
MAPK1 P28482 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
MEN1 O00255 1/20 0.49
TP53 P04637 3/20 0.48
HDAC1 Q13547 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13957031 0.89 P2RX4 (0.66) CYP19A1KMT2AP2RX4MAPK1SMN1; SMN2
SCHEMBL679026 0.85 KMT2A (0.64) CYP19A1MIFCD74SRCKMT2A
SCHEMBL12357944 0.84 CYP19A1 (0.70) CYP19A1MIFCD74SRCKMT2A
SCHEMBL680548 0.82 CYP19A1 (0.49) CYP19A1MIFCD74SRCKMT2A
SCHEMBL14219833 0.81 CYP19A1 (0.47) CYP19A1MIFCD74SRCKMT2A
SCHEMBL27901716 0.81 KMT2A (0.55) KMT2ALMNAMAPK1TP53
SCHEMBL28812266 0.79 KDM4E (0.64) MIFCD74KMT2ALMNASMN1; SMN2
SCHEMBL13957030 0.79 P2RX4 (0.66) CYP19A1KMT2ALMNAP2RX4MAPK1
SCHEMBL7963412 0.78 PLA2G2A (0.65) KMT2ALMNAMAPK1MEN1
SCHEMBL19896424 0.78 CYP19A1 (0.60) CYP19A1SRCKMT2ALMNAP2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053547-B2 Conjugated polymers and blends containing carbazole, representation and use thereof MERCK PATENT GMBH (DE) 2011-11-08 US disclosed
US-20110068304-A1 Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof MERCK PATENT GMBH (DE) 2011-03-24 US disclosed
US-20110068304-A1 Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof MERCK PATENT GMBH (DE) 2011-03-24 US disclosed
US-7834136-B2 Conjugated polymers and blends containing carbazole, representation and use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2010-11-16 US disclosed
US-7834136-B2 Conjugated polymers and blends containing carbazole, representation and use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2010-11-16 US disclosed