Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13265232 | 0.87 | CYP4F2 (0.40) | CYP4F2CYP4A11PKMALDH1A1GAA | |
| SCHEMBL12202099 | 0.86 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL13265175 | 0.83 | CYP4F2 (0.42) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL12203881 | 0.81 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL13263963 | 0.81 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL6745216 | 0.81 | CYP4F2 (0.36) | CYP4F2CYP4A11PKMALDH1A1GAA | |
| SCHEMBL12202110 | 0.79 | CYP4F2 (0.38) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL12202857 | 0.74 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL6798291 | 0.73 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL10164961 | 0.73 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183272-B2 | Indanyl compounds | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-05-22 | — | — | US | disclosed |
| US-20110319359-A1 | INDANYL COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319359-A1 | INDANYL COMPOUNDS | RYR2, ORAI1, CASR | CYP4F2 868/4885CYP4A11 403/4885PKM 3505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.