Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473349 | 0.86 | TSHR (0.44) | ALDH1A1TSHRHPGDALOX15ALOX12 | |
| SCHEMBL7850044 | 0.84 | TSHR (0.43) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14118736 | 0.84 | BCHE (0.46) | ALDH1A1TSHRHPGDMEN1CYP1A2 | |
| SCHEMBL10245222 | 0.84 | TSHR (0.43) | TSHRIDO1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23647056 | 0.82 | IDO1 (0.43) | ALDH1A1TSHRIDO1SLC1A3SLC1A2 | |
| SCHEMBL4722884 | 0.82 | TSHR (0.41) | ALDH1A1TSHRHPGDIDO1SLC1A3 | |
| SCHEMBL11763618 | 0.82 | TSHR (0.41) | ALDH1A1TSHRIDO1SLC1A3SLC1A2 | |
| SCHEMBL22092032 | 0.82 | SLC1A3 (0.42) | ALDH1A1TSHRHPGDIDO1SLC1A3 | |
| SCHEMBL7794286 | 0.82 | TSHR (0.41) | ALDH1A1TSHRHPGDIDO1SLC1A3 | |
| SCHEMBL4519983 | 0.82 | SLC1A3 (0.42) | ALDH1A1TSHRHPGDIDO1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176370-A1 | 3,4-Dihdro-N-[[1-(3-hydroxybutyl)-4-piperidinyl]methyl]-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide as 5-HT(4) receptor antagonist | SMITHKLINE BEECHAM P.L.C. | 2004-09-09 | — | — | US | disclosed |
| WO-2000017207-A1 | 3,4-DIHYDRO -N-[[1-(3 -HYDROXYBUTYL) -4-PIPERIDINYL] METHYL] -2H-[1,3] OXAZINO[3, 2-A]INDOLE -10-CARBOXAMIDE AS 5-HT(4) RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176370-A1 | 3,4-Dihdro-N-[[1-(3-hydroxybutyl)-4-piperidinyl]methyl]-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide as 5-HT(4) receptor antagonist | HTR4, HTR3A, HTR1D | ALDH1A1 870/4885TSHR 426/4885HPGD 912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.