SCHEMBL6800358

SCHEMBL6800358

OP(O)Oc1ccccc1.c1ccc2c(c1)-c1ccccc1-2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.39
TSHR P16473 1/20 0.39
CA5A P35218 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
CA4 P22748 1/20 0.36
NR1H2 P55055 1/20 0.36
BAX Q07812 1/20 0.36
ALDH1A1 P00352 3/20 0.34
RECQL P46063 2/20 0.34
SRC P12931 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
KCNA3 P22001 1/20 0.33
ALOX15 P16050 1/20 0.33
MAPT P10636 2/20 0.32
NSD2 O96028 1/20 0.32
HSP90AA1 P07900 1/20 0.32
HKDC1 Q2TB90 1/20 0.32
TLR9 Q9NR96 1/20 0.32
CA1 P00915 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30275406 0.92 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
SCHEMBL126344 0.92 LTA4H (0.45) LTA4HTSHRCA5ACA5BCA4
SCHEMBL11444642 0.90 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
Hydrochloric Acid SCHEMBL11619305 0.90 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL7767103 0.90 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL23754601 0.90 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
Fluoride SCHEMBL2680499 0.90 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL3257308 0.90 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL1160536 0.90 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4
SCHEMBL4585566 0.90 LTA4H (0.43) LTA4HTSHRCA5ACA5BCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6703507-B2 NONAQUEOUS LIQUID COMPRISING THE AMMONIUM SALT OF A SULFONATED OR CARBOXYLATED PHOSPHITE LIGAND; USE AS A MEDIA FOR CHEMICAL REACTIONS, INCLUDING THOSE USING TRANSITION METAL CATALYSTS CELANESE CHEMICALS EUROPE GMBH (DE) 2004-03-09 US disclosed
US-20020161261-A1 Nonaqueous liquid comprising the ammonium salt of a sulfonated or carboxylated phosphite ligand; use as a media for chemical reactions, including those using transition metal catalysts CELANESE CHEMICALS EUROPE GMBH (DE) 2002-10-31 US disclosed
US-6472565-B1 Method for producing aldehydes CELANESE CHEMICALS EUROPE GMBH (DE) 2002-10-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020161261-A1 Nonaqueous liquid comprising the ammonium salt of a sulfonated or carboxylated phosphite ligand; use as a media for chemical reactions, including those using transition metal catalysts SLC11A2, NSUN2, SSB LTA4H 2027/4885TSHR 3400/4885CA5A 890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.