Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798125 | 0.91 | ESR1 (0.39) | ESR1ESR2TSHRSLC6A4SLC6A3 | |
| SCHEMBL7073179 | 0.88 | ESR1 (0.38) | ESR1ESR2TSHRSLC6A4SLC6A3 | |
| SCHEMBL6794061 | 0.87 | OPRM1 (0.37) | ESR1ESR2DRD2DRD3 | |
| SCHEMBL6795255 | 0.81 | OPRM1 (0.37) | ESR1ESR2DRD2DRD3 | |
| SCHEMBL18408495 | 0.78 | ESR1 (0.45) | ESR1ESR2MAOAMAOBCYP2D6 | |
| SCHEMBL6798568 | 0.73 | OPRM1 (0.39) | ESR1ESR2 | |
| SCHEMBL6794698 | 0.71 | MEN1 (0.40) | ESR1ESR2MAOAMAOBCYP2D6 | |
| SCHEMBL6794695 | 0.70 | OPRM1 (0.37) | ESR1ESR2CYP2D6TSHRSLC6A2 | |
| SCHEMBL6797459 | 0.70 | DRD2 (0.43) | ESR1ESR2DRD2DRD3 | |
| SCHEMBL6796118 | 0.70 | ESR1 (0.42) | ESR1ESR2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082642-A1 | Novel estrogen receptor ligands and method III | MERCK & CO., INC. | 2004-04-29 | — | — | US | claimed |
| US-20040082642-A1 | Novel estrogen receptor ligands and method III | MERCK & CO., INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082642-A1 | Novel estrogen receptor ligands and method III | ESRRA, ESRRB, FSHR | ESR1 19/4885ESR2 5/4885SLC6A9 4480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.