Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 3/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6274486 | 0.91 | FOLH1 (0.43) | HDAC1HDAC3HDAC2NCOR2CRHBP | |
| SCHEMBL6273559 | 0.91 | PTPN2 (0.44) | HDAC1HDAC3HDAC2NCOR2LRRK2 | |
| SCHEMBL6272857 | 0.90 | MEN1 (0.44) | HDAC1HDAC3HDAC2NCOR2CRHBP | |
| SCHEMBL6804388 | 0.88 | CA12 (0.43) | HDAC1HDAC3HDAC2NCOR2CRHBP | |
| SCHEMBL6677469 | 0.79 | POLB (0.50) | LRRK2MEN1KMT2A | |
| SCHEMBL6274189 | 0.79 | MEN1 (0.48) | CRHBPCRHR2RAF1MAP2K1CA12 | |
| SCHEMBL6802977 | 0.78 | CA12 (0.46) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| SCHEMBL6676717 | 0.77 | FOLH1 (0.45) | CRHBPCRHR2RAF1MAP2K1CA12 | |
| SCHEMBL6540329 | 0.77 | TAS2R14 (0.54) | HDAC1HDAC6CA12CA1CA2 | |
| SCHEMBL6677029 | 0.77 | LRRK2 (0.44) | HDAC1LRRK2HDAC6CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | HDAC1 3164/4885HDAC3 3039/4885HDAC2 2822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.