Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677469 | 0.84 | POLB (0.50) | LRRK2MEN1KMT2APOLBLMNA | |
| SCHEMBL6267075 | 0.77 | KMT2A (0.53) | LRRK2MEN1KMT2APOLBLMNA | |
| SCHEMBL6800832 | 0.77 | HDAC1 (0.42) | LRRK2MEN1KMT2AKCNA3CA2 | |
| SCHEMBL6269080 | 0.77 | HTR6 (0.50) | LRRK2MEN1KMT2APOLBLMNA | |
| SCHEMBL6267894 | 0.76 | KMT2A (0.51) | MEN1KMT2APOLBLMNAMAPK1 | |
| SCHEMBL6332076 | 0.75 | CA12 (0.56) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL3148800 | 0.74 | L3MBTL1 (0.56) | LRRK2MEN1KMT2APOLBLMNA | |
| SCHEMBL6271745 | 0.73 | LMNA (0.53) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL6274320 | 0.73 | KMT2A (0.46) | MEN1KMT2APOLBLMNAMAPK1 | |
| SCHEMBL6268955 | 0.73 | MEN1 (0.53) | LRRK2MEN1KMT2ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |