Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28610542 | 0.90 | ALDH1A1 (0.53) | TDP1ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL6806454 | 0.88 | TDP1 (0.46) | TDP1TSHRALDH1A1CYP3A4MEN1 | |
| SCHEMBL3540428 | 0.85 | ALDH1A1 (0.61) | TDP1TSHRALDH1A1CYP3A4MEN1 | |
| SCHEMBL7814797 | 0.84 | HSD17B10 (0.50) | TDP1TSHRALDH1A1CYP3A4MEN1 | |
| SCHEMBL2221806 | 0.84 | HPGD (0.41) | TDP1TSHRALDH1A1CYP3A4MEN1 | |
| SCHEMBL57882 | 0.84 | TSHR (0.40) | TDP1TSHRALDH1A1CYP3A4MEN1 | |
| SCHEMBL27370328 | 0.82 | TDP1 (0.41) | TDP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL10511759 | 0.82 | MAPT (0.41) | TDP1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8522884 | 0.82 | TDP1 (0.41) | TDP1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL1028967 | 0.80 | TDP1 (0.50) | TDP1TSHRALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |