Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27707583 | 0.87 | TDP1 (0.41) | TDP1ALDH1A1ATMMAPTMEN1 | |
| SCHEMBL6806454 | 0.86 | TDP1 (0.46) | TDP1ALDH1A1MAPTMEN1POLB | |
| SCHEMBL10511759 | 0.83 | MAPT (0.41) | TDP1ALDH1A1MAPTMEN1POLB | |
| SCHEMBL27370328 | 0.83 | TDP1 (0.41) | TDP1ALDH1A1MAPTMEN1POLB | |
| SCHEMBL3540428 | 0.83 | ALDH1A1 (0.61) | TDP1ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL6800906 | 0.82 | TDP1 (0.38) | TDP1ALDH1A1MAPTMEN1POLB | |
| SCHEMBL27995417 | 0.81 | FBP1 (0.41) | TDP1ALDH1A1ATMMAPTMEN1 | |
| SCHEMBL15379986 | 0.75 | TDP1 (0.55) | TDP1ALDH1A1ATMMAPTMEN1 | |
| SCHEMBL2331432 | 0.75 | TDP1 (0.71) | TDP1ALDH1A1ATMMAPTPOLB | |
| SCHEMBL29563324 | 0.75 | TDP1 (0.55) | TDP1ALDH1A1ATMMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859042-A | ALOPECIA, ACNE, DISEASES OF THE PROSTATE GLANDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |