Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358559 | 0.81 | TLR7 (0.43) | TLR8TLR7SLC29A1TDP1PDE4D | |
| SCHEMBL6441603 | 0.77 | HSP90AA1 (0.36) | TLR8TLR7ALDH1A1TDP1PDE4A | |
| SCHEMBL3355969 | 0.73 | SMN1; SMN2 (0.38) | TDP1KMT2A | |
| SCHEMBL3352351 | 0.72 | TLR7 (0.73) | TLR8TLR7 | |
| SCHEMBL18587110 | 0.72 | TLR7 (0.46) | TLR8TLR7PDE4DHRH4ADORA2A | |
| SCHEMBL9551426 | 0.71 | TLR7 (0.47) | TLR8TLR7PDE4APDE4BPDE4C | |
| SCHEMBL8125528 | 0.71 | TLR8 (0.56) | TLR8TLR7 | |
| SCHEMBL8150493 | 0.70 | TLR8 (0.37) | TLR8TLR7 | |
| SCHEMBL6439609 | 0.68 | TLR7 (0.40) | TLR8TLR7ALDH1A1KMT2APDE4D | |
| SCHEMBL4791547 | 0.68 | TLR7 (0.42) | TLR8TLR7SLC29A1ALDH1A1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693113-B2 | 2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]napthyridin-4 amine | 3M INNOVATIVE PROPERTIES COMPANY | 2004-02-17 | — | — | US | disclosed |