Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150493 | 0.84 | TLR8 (0.37) | TLR7TLR8 | |
| SCHEMBL6642504 | 0.83 | HDAC4 (0.35) | HSP90AA1HSP90AB1KDM4ECASP1ALDH1A1 | |
| SCHEMBL20865570 | 0.82 | DPP7 (0.32) | HSP90AA1HSP90AB1KDM4ECASP1TLR8 | |
| SCHEMBL3358559 | 0.80 | TLR7 (0.43) | HSP90AA1HSP90AB1HTR2AHTR2BPDE4D | |
| SCHEMBL18546822 | 0.80 | EPHX1 (0.38) | ALDH1A1HIF1A | |
| SCHEMBL6640299 | 0.80 | SHMT2 (0.37) | LMNAKDM4ESHMT2ALDH1A1TP53 | |
| SCHEMBL7095098 | 0.79 | LARS1 (0.32) | HTR2AHTR2BHTR2CCYP1A2LMNA | |
| SCHEMBL6801104 | 0.77 | TLR8 (0.41) | PDE4DPDE4AALDH1A1TLR7ADORA2A | |
| SCHEMBL22006150 | 0.77 | PSMB5 (0.38) | LMNACASP1SHMT2ALDH1A1 | |
| SCHEMBL5669098 | 0.76 | TLR7 (0.44) | HTR2AHTR2BPDE4DKCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1512686-A1 | IMIDAZONAPHTHYRIDINES AND THEIR USE IN INDUCING CYTOKINE BIOSYTHESIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2005-03-09 | — | — | EP | disclosed |
| US-20030212093-A1 | Viricides, antitumor agents | 3M INNOVATIVE PROPERTIES COMPANY | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212093-A1 | Viricides, antitumor agents | IFNG, IFNAR1, MAVS | HSP90AA1 1529/4885HSP90AB1 1937/4885HTR2A 4032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.