Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 11/20 | 0.51 |
| ▸ | HTR1B | P28222 | 10/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR1F | P30939 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795501 | 0.98 | HTR1D (0.53) | HTR1DHTR1BHTR1AHTR1FMTNR1A | |
| SCHEMBL7220850 | 0.83 | HTR1D (0.54) | HTR1DHTR1BHTR1AHTR1FCCR2 | |
| SCHEMBL6907469 | 0.83 | HTR1D (0.51) | HTR1DHTR1BHTR1AHTR1FOPRM1 | |
| SCHEMBL6796075 | 0.83 | HTR1D (0.60) | HTR1DHTR1BHTR1AHTR1FOPRM1 | |
| SCHEMBL6794901 | 0.81 | MTNR1A (0.46) | HTR1DHTR1BHTR1AHTR1FMTNR1A | |
| SCHEMBL6795113 | 0.81 | MTNR1A (0.46) | HTR1DHTR1BHTR1AHTR1FMTNR1A | |
| SCHEMBL6795296 | 0.81 | MTNR1A (0.46) | HTR1DHTR1BHTR1AHTR1FMTNR1A | |
| SCHEMBL6795203 | 0.81 | MTNR1A (0.46) | HTR1DHTR1BHTR1AHTR1FMTNR1A | |
| SCHEMBL6796026 | 0.81 | HTR1D (0.48) | HTR1DHTR1AHTR1FMTNR1AOPRM1 | |
| SCHEMBL6796369 | 0.80 | OPRM1 (0.46) | HTR1DHTR1BOPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743808-B1 | PSYCHOLOGICAL AND NEUROLOGIC DISORDERS; CENTRAL SEROTONERGIC 5-HT1A AND 5-HT2A RECEPTOR ANTAGONISTS | H. LUNDBECK A/S (DK) | 2004-06-01 | — | — | US | disclosed |