Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27545499 | 0.89 | MEN1 (0.54) | MEN1KMT2ANPC1PDK1PDK2 | |
| SCHEMBL6801408 | 0.83 | MEN1 (0.55) | MEN1KMT2ANPC1PDK1PDK2 | |
| SCHEMBL6799435 | 0.81 | MEN1 (0.72) | MEN1KMT2ANPC1PDK1PDK2 | |
| SCHEMBL6802630 | 0.81 | MEN1 (0.55) | MEN1KMT2ANPC1PDK1PDK2 | |
| SCHEMBL6802291 | 0.80 | MEN1 (0.76) | MEN1KMT2ANPC1PDK1PDK2 | |
| SCHEMBL6798512 | 0.79 | MEN1 (0.55) | MEN1KMT2ANPC1PDK1PDK2 | |
| SCHEMBL28310730 | 0.78 | MEN1 (0.63) | MEN1KMT2ANPC1ALDH1A1POLB | |
| SCHEMBL28311575 | 0.78 | KMT2A (0.63) | MEN1KMT2ANPC1ALDH1A1NPSR1 | |
| SCHEMBL28627387 | 0.76 | MEN1 (0.76) | MEN1KMT2ANPC1PDK1ALDH1A1 | |
| SCHEMBL6799801 | 0.74 | GAA (0.62) | MEN1KMT2ANPC1PDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |