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Sugi Predict / Targets / CACNG5

CACNG5

Voltage-dependent calcium channel gamma-5 sub · Q9UF02 · CACNG5 on Sugi Atlas →

5,900 patent compounds predicted against CACNG5, 2,268 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL116362 SCHEMBL116362 0.45 11/20
SCHEMBL6121858 SCHEMBL6121858 0.52 9/20
SCHEMBL2585915 SCHEMBL2585915 0.51 8/20
SCHEMBL3354274 SCHEMBL3354274 0.62 7/20
SCHEMBL3357851 SCHEMBL3357851 0.54 7/20
SCHEMBL4750473 SCHEMBL4750473 0.52 7/20
SCHEMBL3350921 SCHEMBL3350921 0.49 7/20
SCHEMBL619154 SCHEMBL619154 0.41 7/20
SCHEMBL620978 SCHEMBL620978 0.40 7/20
SCHEMBL621013 SCHEMBL621013 0.40 7/20
SCHEMBL5428566 SCHEMBL5428566 0.52 6/20
SCHEMBL621555 SCHEMBL621555 0.39 6/20
SCHEMBL617973 SCHEMBL617973 0.38 6/20
SCHEMBL7053553 SCHEMBL7053553 0.62 5/20
SCHEMBL4405461 SCHEMBL4405461 0.55 5/20
SCHEMBL4399845 SCHEMBL4399845 0.54 5/20
SCHEMBL4967687 SCHEMBL4967687 0.51 5/20
SCHEMBL1810921 SCHEMBL1810921 0.51 5/20
SCHEMBL4399843 SCHEMBL4399843 0.50 5/20
SCHEMBL3477582 SCHEMBL3477582 0.47 5/20

Clinical trials — most relevant to CACNG5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Effect of Pregabalin and Etoricoxib on Pain Alone Versus in Combination PHASE4UNKNOWN
Role of Intralipid in Management of Organophosphorus Poisoning PHASE2/PHASE3WITHDRAWN
Analgesic Potentials of Preoperative Pregabalin,Magnesium Sulphate and Their Combination in Acute Post-thoracotomy Pain PHASE3COMPLETED
The Re-Prosper HF Study PHASE2/PHASE3COMPLETED
Dronabinol in Trichotillomania and Other Body Focused Repetitive Behaviors PHASE2/PHASE3COMPLETED
Valproic Acid (VPA) for Acute Kidney Injury (AKI) in Liver Transplant Patients PHASE2WITHDRAWN
Population Pharmacokinetic-pharmacodynamic (PK-PD) Modeling of Co-administered Gabapentin in Neuropathic Pain PHASE2COMPLETED
Valproic Acid (VPA) for Acute Kidney Injury (AKI) in Trauma Patients PHASE2WITHDRAWN
4-Aminopyridine in Episodic Ataxia Type 2 PHASE2WITHDRAWN
Ultra-Early Gamma Knife Stereotactic Radiosurgery for TN PHASE2RECRUITING
Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease PHASE2COMPLETED
Physiologic Effects of Topiramate on Cognition PHASE1COMPLETED
MRI-phenotyping of Patients With Pathogenic Anoctamin 5 Variants nanRECRUITING
Sodium Channel Splicing in Heart Failure Trial (SOCS-HEFT) Prospective Study nanUNKNOWN
Sodium Channel Splicing in Heart Failure Trial nanCOMPLETED
Genetic Determinants of Sudden Cardiac Death nanCOMPLETED
Molecular and Cellular Characterization of Cardiac Tissue in Postnatal Development nanRECRUITING
Factors Affecting Salt Intake in Young Adults nanUNKNOWN
Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services nanUNKNOWN
Evaluation of the Effects of KCNQ1 Mutation on Insulin Tolerance and Obsessive Compulsive Features in Long QT Romano-Ward Syndrome Patients. nanUNKNOWN
Pregabalin Phonophoresis and MET for Knee Osteoarthritis nanRECRUITING
Functional Study of Inhibitory Neurotransmission in the Human Epileptic Brain. nanRECRUITING
Exploring the Genetics of Neuropathic Pain nanRECRUITING
Worm Study: Modifier Genes in Sudden Cardiac Death nanUNKNOWN
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic, Inflammatory and Takotsubo Cardiomyopathy (MEMORY) nanCOMPLETED
Pharmacogenetics and Cardiovascular Events nanCOMPLETED
ST-segment Elevation as an AF Endophenotype nanCOMPLETED
Calcium Channel Splice Variant Expression in Cardiovascular Disease and Aging nanCOMPLETED
Cenobamate Expanded Access Program (EAP) nanAPPROVED_FOR_MARKETING
Neurogenic Mechanisms in Burning Mouth Syndrome nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a CACNG5 binder may also engage these)

ProteinNameSimilarity
Q8VHW4 — 1.000 Q8VHW4 →
Q8VHW8 — 1.000 Q8VHW8 →
P62956 — 0.985 P62956 →
CACNG7 Voltage-dependent calcium channel gamma-7 sub 0.985 landscape →
P62957 — 0.980 P62957 →
Q8VHW9 — 0.961 Q8VHW9 →
Q86UP9 — 0.961 Q86UP9 →
CACNG1 Voltage-dependent calcium channel gamma-1 sub 0.960 landscape →
Q7Z7J7 — 0.959 Q7Z7J7 →
Q9JJV4 — 0.957 Q9JJV4 →
Q5JRV8 — 0.956 Q5JRV8 →
CACNG4 Voltage-dependent calcium channel gamma-4 sub 0.956 landscape →
Q9CTN8 — 0.956 Q9CTN8 →
Q9BE63 — 0.955 Q9BE63 →
Q9XT98 — 0.954 Q9XT98 →
Q1L8F4 — 0.954 Q1L8F4 →
Q7TSY2 — 0.953 Q7TSY2 →
H3BS89 — 0.953 H3BS89 →
Q8BHW5 — 0.953 Q8BHW5 →
Q7TMP6 — 0.951 Q7TMP6 →
Q5E9L0 — 0.951 Q5E9L0 →
Q5U4E0 — 0.950 Q5U4E0 →
Q8NBL3 — 0.948 Q8NBL3 →
Q9Z0S6 — 0.948 Q9Z0S6 →
Q68FV0 — 0.948 Q68FV0 →
Q9CZ16 — 0.947 Q9CZ16 →
Q9Y5I7 — 0.947 Q9Y5I7 →
Q17R16 — 0.947 Q17R16 →
Q8BM86 — 0.945 Q8BM86 →
A4IF75 — 0.945 A4IF75 →