Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | BCR | P11274 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FABP1 | P07148 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658514 | 0.84 | PTGS2 (0.62) | PTGS2KDM4EALDH1A1RAB9AALOX5AP | |
| SCHEMBL937206 | 0.84 | PTGS2 (0.61) | PTGS2KDM4EALDH1A1RAB9AHSD11B1 | |
| SCHEMBL29415408 | 0.84 | PTGS2 (0.61) | PTGS2KDM4EALDH1A1RAB9AHSD11B1 | |
| SCHEMBL890902 | 0.82 | ABL1 (0.48) | ABL1ABCB1BCRRAB9AFABP1 | |
| SCHEMBL7265178 | 0.82 | PTGS2 (0.50) | PTGS2KDM4EALDH1A1RAB9ABAZ2B | |
| Hydrochloric Acid SCHEMBL7352630 | 0.82 | PTGS2 (0.59) | PTGS2KDM4EALDH1A1RAB9AHSD11B1 | |
| SCHEMBL2447766 | 0.82 | PTGS2 (0.64) | PTGS2KDM4EALDH1A1RAB9A | |
| SCHEMBL6901981 | 0.81 | PTGS2 (0.68) | PTGS2KDM4EALDH1A1RAB9AALOX5AP | |
| SCHEMBL6904881 | 0.81 | PTGS2 (0.68) | PTGS2KDM4EALDH1A1RAB9AALOX5AP | |
| SCHEMBL3830209 | 0.81 | PTGS2 (0.48) | PTGS2KDM4EALDH1A1RAB9AALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092517-A1 | Phenyl derivatives and their use in the treatment of thromboembolic disorders or tumours | MERCK PATENT GMBH (DE) | 2004-05-13 | — | — | US | disclosed |
| EP-1370522-A1 | PHENYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISORDERS OR TUMOURS | MERCK PATENT GmbH (DE) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002070471-A1 | PHENYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISORDERS OR TUMOURS | MERCK PATENT GMBH (DE) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092517-A1 | Phenyl derivatives and their use in the treatment of thromboembolic disorders or tumours | RCOR3, F2, NCOR2 | PTGS2 380/4885ABL1 3501/4885ABCB1 1875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.