Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | MEN1 | O00255 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879472 | 0.90 | MEN1 (0.68) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL16486952 | 0.79 | L3MBTL1 (0.73) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL31098648 | 0.77 | MEN1 (0.82) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL14359092 | 0.77 | MAPT (0.73) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL11696466 | 0.76 | TDP1 (0.56) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL8353349 | 0.75 | MEN1 (1.00) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL6002470 | 0.75 | MAPT (0.73) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL243259 | 0.75 | MEN1 (1.00) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL293916 | 0.74 | MAPT (0.72) | MAPTMEN1KMT2AMAPK1TDP1 | |
| Water SCHEMBL22157648 | 0.72 | MEN1 (0.69) | MAPTMEN1KMT2AMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | AJINOMOTO CO. INC | 2004-01-01 | — | — | US | claimed |
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | AJINOMOTO CO. INC | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | NFKBIA, IKBKB, CHUK | MAPT 1447/4885MEN1 4653/4885KMT2A 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.