Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | MAPT | P10636 | 8/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801880 | 0.90 | MAPT (0.59) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL31098648 | 0.87 | MEN1 (0.82) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL293916 | 0.84 | MAPT (0.72) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL14359092 | 0.83 | MAPT (0.73) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL16486952 | 0.83 | L3MBTL1 (0.73) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL31715811 | 0.83 | MAPT (0.73) | MEN1KMT2AMAPTMAPK1TDP1 | |
| Water SCHEMBL22157648 | 0.82 | MEN1 (0.69) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL2328147 | 0.81 | MEN1 (0.73) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL8353349 | 0.81 | MEN1 (1.00) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL243259 | 0.81 | MEN1 (1.00) | MEN1KMT2AMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981145-A | CONTAINING A COPOLYMER OF MODIFIED HYDROXYSTYRENE MONOMER AND AN ETHYLENICALLY UNSATURATED MONOMER FREE OF AROMATIC RING, SUITABLE FOR ANTIREFLECTIVE COATING | CLARIANT FINANCE (BVI) LIMITED (VG) | 1999-11-09 | — | — | US | claimed |
| US-4213898-A | FOR POLYACRYLONITRILE | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | claimed |
| US-3998803-A | TEXTILES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1976-12-21 | — | — | US | claimed |
| US-7109215-B2 | Compounds possessing neuronal activity | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2006-09-19 | — | — | US | disclosed |
| US-20020013351-A1 | Compounds possessing neuronal activity | VERTEX PHARMACEUTICALS INCORPORATED | 2002-01-31 | — | — | US | disclosed |
| US-6268384-B1 | DO NOT BIND TO FKBP, AND WHICH DO NOT HAVE MULTI-DRUG RESISTANCE REVERSAL ACTIVITY. | VERTEX PHARMACEUTICALS INCORPORATED | 2001-07-31 | — | — | US | disclosed |
| EP-1007521-A1 | COMPOUNDS POSSESSING NEURONAL ACTIVITY | Vertex Pharmaceuticals Incorporated (US) | 2000-06-14 | — | — | EP | disclosed |
| WO-1999010340-A1 | COMPOUNDS POSSESSING NEURONAL ACTIVITY | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1999-03-04 | — | — | WO | disclosed |
| US-4213898-A | FOR POLYACRYLONITRILE | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | disclosed |
| US-4032532-A | AZO DYES | SANDOZ LTD. (CH) | 1977-06-28 | — | — | US | disclosed |
| US-3998803-A | TEXTILES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013351-A1 | Compounds possessing neuronal activity | BDNF, NGF, GAP43 | MEN1 3557/4885KMT2A 4469/4885MAPT 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.