SCHEMBL6802128

SCHEMBL6802128

CCC1(C(N)=O)CCC(N)CC1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.32
GNAO1 P09471 1/20 0.32
GNAI1 P63096 1/20 0.32
SMYD3 Q9H7B4 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL578419 0.83 JAK2 (0.31) SMN1; SMN2
SCHEMBL6979479 0.83 CYP2C19 (0.33) GNAI3GNAO1GNAI1SMYD3
SCHEMBL17110192 0.83 GNAI3 (0.32) GNAI3GNAO1GNAI1SMYD3
SCHEMBL1768062 0.82
Hydrochloric Acid SCHEMBL385319 0.82 GNAI3 (0.34) GNAI3GNAO1GNAI1SMYD3
Hydrochloric Acid SCHEMBL385321 0.82 GNAI3 (0.34) GNAI3GNAO1GNAI1SMYD3
Hydrochloric Acid SCHEMBL27793068 0.80
SCHEMBL9603340 0.80 GNAI3 (0.41) GNAI3GNAO1GNAI1
SCHEMBL1810305 0.78 CYP2C19 (0.38) SMN1; SMN2
SCHEMBL1768081 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063701-A1 Piperidine derivatives and anti-platelet agents containing the same AJINOMOTO CO., INC (JP) 2004-04-01 US claimed
US-20020147195-A1 Piperidine derivatives and anti-platelet agents containing the same AJINOMOTO CO., INC. (JP) 2002-10-10 US claimed
US-20020019533-A1 PIPERIDINE DERIVATIVES AND ANTI-PLATELET AGENTS CONTAINING THE SAME MAKINO SHINGO (JP) 2002-02-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019533-A1 PIPERIDINE DERIVATIVES AND ANTI-PLATELET AGENTS CONTAINING THE SAME HTR2A, PDGFRA, PDGFRB GNAI3 1321/4885GNAO1 2039/4885GNAI1 1353/4885
US-20020147195-A1 Piperidine derivatives and anti-platelet agents containing the same HTR2A, PDGFRA, PDGFRB GNAI3 1321/4885GNAO1 2039/4885GNAI1 1353/4885
US-20040063701-A1 Piperidine derivatives and anti-platelet agents containing the same HTR2A, PDGFRA, PDGFRB GNAI3 1321/4885GNAO1 2039/4885GNAI1 1353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.