Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803894 | 0.80 | NT5E (0.44) | HPGDCYP3A4CYP2C9ALDH1A1CYP1A2 | |
| SCHEMBL13202017 | 0.74 | KMT2A (0.52) | HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6804444 | 0.74 | FGFR1 (0.55) | HPGDMEN1KMT2A | |
| SCHEMBL29930250 | 0.73 | ALDH1A1 (0.62) | HPGDCYP3A4CYP2C9ALDH1A1CYP1A2 | |
| SCHEMBL1634757 | 0.73 | ALDH1A1 (0.62) | HPGDCYP3A4CYP2C9ALDH1A1CYP1A2 | |
| SCHEMBL6801219 | 0.72 | FGFR1 (0.57) | HPGDALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL6799091 | 0.71 | IDO1 (0.46) | HPGDCYP3A4MEN1KMT2A | |
| SCHEMBL14910623 | 0.70 | NPC1 (0.51) | HPGDCYP3A4CYP2C9ALDH1A1CYP1A2 | |
| SCHEMBL19350803 | 0.69 | FGFR1 (0.43) | HPGDALDH1A1KMT2ASMN1; SMN2HTT | |
| SCHEMBL29623847 | 0.69 | FGFR1 (0.43) | HPGDALDH1A1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723735-B1 | TREATMENT OR PREVENTION OF ANXIETY | MERCK SHARP & DOHME LTD. | 2004-04-20 | — | — | US | disclosed |
| EP-1214319-B1 | IMIDAZO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME (GB) | 2003-11-26 | — | — | EP | disclosed |