Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 18/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807862 | 0.79 | F10 (0.63) | F10KLKB1 | |
| SCHEMBL6807158 | 0.77 | F10 (0.42) | F10NPC1RAB9A | |
| SCHEMBL890803 | 0.74 | F10 (0.47) | F10 | |
| SCHEMBL891101 | 0.73 | F10 (0.52) | F10KLKB1 | |
| SCHEMBL891124 | 0.70 | F10 (0.47) | F10KLKB1NPC1RAB9A | |
| SCHEMBL157569 | 0.69 | F10 (0.47) | KDM4EF10NPC1RAB9A | |
| SCHEMBL6712468 | 0.68 | F10 (0.40) | F10 | |
| SCHEMBL10178317 | 0.66 | F10 (0.75) | F10KLKB1 | |
| SCHEMBL890814 | 0.64 | TSHR (0.35) | GAA | |
| SCHEMBL30271022 | 0.64 | L3MBTL1 (0.65) | KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067938-A1 | Quaternary amines and related inhibitors of factor xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067938-A1 | Quaternary amines and related inhibitors of factor xa | F12, TFPI, F11 | KDM4E 645/4885GAA 1113/4885F10 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.