SCHEMBL6802637

SCHEMBL6802637

CNC(=O)C(Cc1ccc(NS(=O)(=O)O)cc1)NC(=O)CCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTPRB P23467 13/20 0.57
HDAC8 Q9BY41 2/20 0.52
HDAC3 O15379 1/20 0.52
HDAC4 P56524 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC10 Q969S8 1/20 0.52
HDAC11 Q96DB2 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
HDAC9 Q9UKV0 1/20 0.52
HDAC5 Q9UQL6 1/20 0.52
MMP1 P03956 3/20 0.49
MMP3 P08254 2/20 0.49
GRIA1 P42261 1/20 0.49
MMP2 P08253 1/20 0.49
MMP7 P09237 1/20 0.49
FCER2 P06734 1/20 0.49
MMP9 P14780 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6803291 1.00 PTPRB (0.57) PTPRBHDAC8HDAC3HDAC4HDAC1
SCHEMBL6802626 1.00 PTPRB (0.57) PTPRBHDAC8HDAC3HDAC4HDAC1
SCHEMBL6803112 0.88 CTSL (0.56) PTPRBHDAC8HDAC3HDAC4HDAC1
SCHEMBL6917607 0.84 PTPRB (0.46) PTPRBHDAC8HDAC3HDAC4HDAC1
SCHEMBL6917602 0.84 PTPRB (0.46) PTPRBHDAC8HDAC3HDAC4HDAC1
SCHEMBL6796079 0.83 GRIA1 (0.51) PTPRBMMP1MMP3GRIA1MMP2
SCHEMBL6796074 0.83 GRIA1 (0.51) PTPRBMMP1MMP3GRIA1MMP2
SCHEMBL6803683 0.82 CTSL (0.54) PTPRBHDAC8HDAC3HDAC4HDAC1
SCHEMBL6803693 0.82 CTSL (0.54) PTPRBHDAC8HDAC3HDAC4HDAC1
SCHEMBL6801668 0.82 ANPEP (0.60) PTPRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074238-A1 PHENETHYLAMINO SULFAMIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO claimed
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US claimed
WO-2004074238-A1 PHENETHYLAMINO SULFAMIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO disclosed
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167183-A1 Phenethylamino sulfamic acids PTPRM, PTPRS, PTPRE PTPRB 13/4885HDAC8 3002/4885HDAC3 3494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.