SCHEMBL6803112

SCHEMBL6803112

CNC(=O)[C@H](Cc1ccc(NS(=O)(=O)O)cc1)NC(=O)Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.56
CTSB P07858 1/20 0.56
CTSS P25774 1/20 0.56
PTPRB P23467 14/20 0.56
FCER2 P06734 2/20 0.51
MMP1 P03956 1/20 0.51
HDAC3 O15379 1/20 0.51
HDAC4 P56524 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC7 Q8WUI4 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC10 Q969S8 1/20 0.51
HDAC11 Q96DB2 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
HDAC9 Q9UKV0 1/20 0.51
HDAC5 Q9UQL6 1/20 0.51
CHRNA1 P02708 1/20 0.50
CHRNG P07510 1/20 0.50
CHRNB1 P11230 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6803291 0.88 PTPRB (0.57) PTPRBFCER2MMP1HDAC3HDAC4
SCHEMBL6802637 0.88 PTPRB (0.57) PTPRBFCER2MMP1HDAC3HDAC4
SCHEMBL6802626 0.88 PTPRB (0.57) PTPRBFCER2MMP1HDAC3HDAC4
SCHEMBL6803683 0.84 CTSL (0.54) CTSLCTSSPTPRBHDAC3HDAC4
SCHEMBL6803693 0.84 CTSL (0.54) CTSLCTSSPTPRBHDAC3HDAC4
SCHEMBL6801389 0.84 CTSL (0.53) CTSLCTSBCTSSPTPRBFCER2
SCHEMBL6801392 0.84 CTSL (0.53) CTSLCTSBCTSSPTPRBFCER2
SCHEMBL6801678 0.84 ANPEP (0.60) PTPRB
SCHEMBL6801668 0.84 ANPEP (0.60) PTPRB
SCHEMBL3478166 0.83 CTSL (0.58) CTSLCTSBCTSSPTPRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074238-A1 PHENETHYLAMINO SULFAMIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO claimed
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US claimed
WO-2004074238-A1 PHENETHYLAMINO SULFAMIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO disclosed
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167183-A1 Phenethylamino sulfamic acids PTPRM, PTPRS, PTPRE CTSL 2677/4885CTSB 2219/4885CTSS 1861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.