Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.66 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.66 |
| ▸ | BRD4 | O60885 | 1/20 | 0.64 |
| ▸ | BCL2 | P10415 | 1/20 | 0.62 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.62 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.62 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6613755 | 0.94 | TERT (0.77) | TERTCYP1A2CYP3A4CYP2C19NCOA1 | |
| SCHEMBL6614290 | 0.91 | TERT (0.73) | TERTBRD4BCL2CSNK2A2CSNK2B | |
| SCHEMBL6614365 | 0.90 | TERT (0.80) | TERTCYP1A2CYP3A4CYP2C19NCOA1 | |
| SCHEMBL6613454 | 0.89 | TERT (1.00) | TERTCYP3A4CYP2C19BRD4CSNK2A2 | |
| SCHEMBL6797692 | 0.88 | CYP3A4 (0.66) | TERTCYP1A2CYP3A4CYP2C19NCOA1 | |
| SCHEMBL988001 | 0.87 | TERT (0.77) | TERTCYP1A2CYP3A4CYP2C19NCOA1 | |
| SCHEMBL29612043 | 0.87 | TERT (0.77) | TERTCYP1A2CYP3A4CYP2C19NCOA1 | |
| SCHEMBL6617685 | 0.86 | CSNK2A2 (0.74) | TERTCYP3A4CYP2C19CSNK2A2CSNK2B | |
| SCHEMBL6617350 | 0.84 | TERT (0.65) | TERTCYP1A2CYP3A4CYP2C19NCOA1 | |
| SCHEMBL6614126 | 0.84 | TERT (1.00) | TERTCYP3A4CYP2C19BRD4CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063665-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2004-04-01 | — | — | US | claimed |
| US-20020160983-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2002-10-31 | — | — | US | claimed |
| US-20040063665-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2004-04-01 | — | — | US | disclosed |
| US-20020160983-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020160983-A1 | Substituted benzopyranones as telomerase inhibitors | TERT, TERF2, TERF2IP | TERT 1/4885CYP1A2 3159/4885CYP3A4 3385/4885 |
| US-20040063665-A1 | Substituted benzopyranones as telomerase inhibitors | TERT, TERF2, TERF2IP | TERT 1/4885CYP1A2 3209/4885CYP3A4 3411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.