SCHEMBL6803183

SCHEMBL6803183

CCNC(=O)CCCNC=O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.53
ADH1B P00325 3/20 0.50
ADH1A P07327 3/20 0.50
ADH7 P40394 3/20 0.50
ADH1C P00326 2/20 0.50
EPHX1 P07099 1/20 0.48
ADH4 P08319 1/20 0.48
CASP2 P42575 1/20 0.42
EPHX2 P34913 3/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NAAA Q02083 1/20 0.40
CAPN1 P07384 1/20 0.40
SLC6A5 Q9Y345 1/20 0.38
CNR1 P21554 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6025053 0.88 FAAH (0.47) FAAHADH1BADH1AADH7ADH1C
SCHEMBL21172672 0.79 CASP2 (0.47) FAAHADH1BADH1AADH7ADH1C
SCHEMBL10380841 0.79 CASP2 (0.61) FAAHADH1BADH1AADH7ADH1C
SCHEMBL22242831 0.78 CASP2 (0.66) FAAHADH1BADH1AADH7ADH1C
SCHEMBL17347892 0.78 EPHX2 (0.53) FAAHCASP2EPHX2MEN1KMT2A
SCHEMBL9618659 0.78 FAAH (0.81) FAAHCASP2EPHX2MEN1KMT2A
SCHEMBL12346213 0.78 FAAH (0.73) FAAHCASP2EPHX2MEN1KMT2A
SCHEMBL21972589 0.78 FAAH (0.61) FAAHEPHX2MEN1KMT2ASLC6A5
SCHEMBL23735383 0.77 KDM4E (0.54) FAAHADH1BADH1AADH7ADH1C
SCHEMBL1832239 0.77 FAAH (0.59) FAAHCASP2EPHX2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063701-A1 Piperidine derivatives and anti-platelet agents containing the same AJINOMOTO CO., INC (JP) 2004-04-01 US claimed
US-20020147195-A1 Piperidine derivatives and anti-platelet agents containing the same AJINOMOTO CO., INC. (JP) 2002-10-10 US claimed
US-20020019533-A1 PIPERIDINE DERIVATIVES AND ANTI-PLATELET AGENTS CONTAINING THE SAME MAKINO SHINGO (JP) 2002-02-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019533-A1 PIPERIDINE DERIVATIVES AND ANTI-PLATELET AGENTS CONTAINING THE SAME HTR2A, PDGFRA, PDGFRB FAAH 556/4885ADH1B 4830/4885ADH1A 2869/4885
US-20020147195-A1 Piperidine derivatives and anti-platelet agents containing the same HTR2A, PDGFRA, PDGFRB FAAH 556/4885ADH1B 4830/4885ADH1A 2869/4885
US-20040063701-A1 Piperidine derivatives and anti-platelet agents containing the same HTR2A, PDGFRA, PDGFRB FAAH 556/4885ADH1B 4830/4885ADH1A 2869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.