⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288776 | 1.00 | — | — | |
| SCHEMBL14288775 | 1.00 | — | — | |
| SCHEMBL13959962 | 0.90 | KISS1R (0.34) | — | |
| SCHEMBL2246543 | 0.81 | — | — | |
| SCHEMBL12657391 | 0.78 | — | — | |
| SCHEMBL15678003 | 0.77 | — | — | |
| SCHEMBL13989307 | 0.76 | HTT (0.50) | — | |
| SCHEMBL3016246 | 0.75 | GABRR1 (0.39) | — | |
| SCHEMBL17677147 | 0.75 | GABRR1 (0.39) | — | |
| SCHEMBL11731071 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772009-A | Novel amide-ester ashless friction improver and preparation method thereof | 中国科学院上海有机化学研究所 | 2024-10-15 | — | — | CN | claimed |
| CN-118772007-A | Novel ether-amide ashless additive and preparation method thereof | 中国科学院上海有机化学研究所 | 2024-10-15 | — | — | CN | claimed |
| US-7060700-B2 | Amide derivatives useful as inhibitors of the production of cytokines | ASTRAZENECA AB (SE) | 2006-06-13 | — | — | US | claimed |
| US-20030105142-A1 | Amide derivatives useful as inhibitors of the production of cytokines | ASTRAZENECA AB | 2003-06-05 | — | — | US | claimed |
| US-6500912-B1 | Epoxy resin system | RESOLUTION PERFORMANCE PRODUCTS LLC | 2002-12-31 | — | — | US | claimed |
| US-6432949-B1 | Amide derivatives useful as inhibitors of the production of cytokines | ASTRAZENECA AB (SE) | 2002-08-13 | — | — | US | claimed |
| EP-1102750-A1 | AMIDE DERIVATIVES USEFUL AS INHIBITORS OF THE PRODUCTION OF CYTOKINES | AstraZeneca AB (SE) | 2001-05-30 | — | — | EP | claimed |
| WO-2000007991-A1 | AMIDE DERIVATIVES USEFUL AS INHIBITORS OF THE PRODUCTION OF CYTOKINES | ASTRAZENECA AB (SE) | 2000-02-17 | — | — | WO | claimed |
| CN-120157677-A | Bridged-ring organic polyamine, preparation method and application | 大连理工大学 | 2025-06-17 | — | — | CN | disclosed |
| CN-118772009-A | Novel amide-ester ashless friction improver and preparation method thereof | 中国科学院上海有机化学研究所 | 2024-10-15 | — | — | CN | disclosed |
| CN-118772007-A | Novel ether-amide ashless additive and preparation method thereof | 中国科学院上海有机化学研究所 | 2024-10-15 | — | — | CN | disclosed |
| US-20230373903-A1 | CATIONIC LIPIDS AND TRANSFECTION METHODS | FACTOR BIOSCIENCE INC. | 2023-11-23 | — | — | US | disclosed |
| US-20230193277-A1 | NUCLEIC ACID, PHARMACEUTICAL COMPOSITION, CONJUGATE, PREPARATION METHOD, AND USE | Suzhou Ribo Life Science Co., Ltd. (CN) | 2023-06-22 | — | — | US | disclosed |
| US-11597699-B2 | MEK inhibitors and methods of their use | EXELIXIS, INC. (US) | 2023-03-07 | — | — | US | disclosed |
| WO-2000020402-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2000-04-13 | — | — | WO | disclosed |
| WO-2000018738-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2000-04-06 | — | — | WO | disclosed |
| WO-2000007991-A1 | AMIDE DERIVATIVES USEFUL AS INHIBITORS OF THE PRODUCTION OF CYTOKINES | ASTRAZENECA AB (SE) | 2000-02-17 | — | — | WO | disclosed |
| WO-2000007980-A1 | AMIDE DERIVATIVES WHICH ARE USEFUL AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2000-02-17 | — | — | WO | disclosed |
| US-5928633-A | PASSING ANTIGEN-CONTAINING SUBSTANCE THROUGH MATERIAL CONTAINING UREA BONDS OR THIOUREA BONDS AND GROUPS CAPABLE OF FORMING HYDROGEN BONDS | TORAY INDUSTRIES, INC. (JP) | 1999-07-27 | — | — | US | disclosed |
| EP-0743067-A2 | Use of urea and thiourea compounds for elimination or detoxofication of superantigens from body fluids | TORAY INDUSTRIES, INC. (JP) | 1996-11-20 | — | — | EP | disclosed |