Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | SCN1A | P35498 | 3/20 | 0.58 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.58 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | HTR3A | P46098 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10426263 | 0.99 | KDM4E (0.60) | KDM4EALDH1A1LMNACYP2D6CYP1A2 | |
| SCHEMBL5102530 | 0.86 | CYP2D6 (0.59) | KDM4EALDH1A1LMNACYP2D6CYP1A2 | |
| SCHEMBL1734452 | 0.85 | CYP2D6 (0.65) | KDM4EALDH1A1LMNACYP2D6CYP1A2 | |
| SCHEMBL11242982 | 0.84 | MCHR1 (0.66) | KDM4EALDH1A1LMNACYP2D6CYP1A2 | |
| SCHEMBL6803935 | 0.84 | MCHR1 (0.59) | KDM4EALDH1A1LMNACYP2D6CYP1A2 | |
| SCHEMBL10589183 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1LMNACYP2D6CYP1A2 | |
| SCHEMBL6807627 | 0.80 | CYP2D6 (0.53) | KDM4EALDH1A1LMNACYP2D6CYP1A2 | |
| SCHEMBL10426054 | 0.80 | ABCB1 (0.52) | KDM4EALDH1A1LMNACYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL11340459 | 0.79 | CYP3A4 (0.59) | KDM4EALDH1A1LMNACYP3A4TSHR | |
| SCHEMBL11233185 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1LMNACYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063686-A1 | Carboxamide compounds and their use as antagonists of a human 11cby receptor | JOHNSON CHRISTOPHER NORBERT (GB) | 2004-04-01 | — | — | US | disclosed |
| EP-1305304-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF A HUMAN 11CBY RECEPTOR | SMITHKLINE BEECHAM PLC (GB) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002010146-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF A HUMAN 11CBY RECEPTOR | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-07 | — | — | WO | disclosed |
| US-4906634-A | Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents | SCHERING A.G. (DE) | 1990-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063686-A1 | Carboxamide compounds and their use as antagonists of a human 11cby receptor | CNR1, GPR3, CCKAR | KDM4E 2413/4885ALDH1A1 1692/4885LMNA 2527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.