Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | SCN1A | P35498 | 3/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242982 | 0.91 | MCHR1 (0.66) | MCHR1KDM4EALDH1A1LMNAMAOB | |
| SCHEMBL6803941 | 0.84 | KDM4E (0.61) | MCHR1KDM4EALDH1A1LMNAMAOB | |
| SCHEMBL6807626 | 0.84 | MCHR1 (0.57) | MCHR1KDM4EALDH1A1LMNACYP2D6 | |
| Bromide SCHEMBL10426263 | 0.83 | KDM4E (0.60) | MCHR1KDM4EALDH1A1LMNAMAOB | |
| SCHEMBL6811199 | 0.83 | MAPK1 (0.68) | MCHR1CYP2D6CYP1A2SCN1ASCN2A | |
| SCHEMBL30969248 | 0.83 | MAPK1 (0.68) | MCHR1CYP2D6CYP1A2SCN1ASCN2A | |
| SCHEMBL6811996 | 0.80 | MCHR1 (0.60) | MCHR1KDM4EALDH1A1LMNACYP2D6 | |
| SCHEMBL30969296 | 0.79 | PRSS1 (0.56) | KDM4EALDH1A1LMNACYP2D6CYP1A2 | |
| SCHEMBL10425884 | 0.77 | ALDH1A1 (0.56) | MCHR1KDM4EALDH1A1LMNAMAOB | |
| Hypochlorous Acid SCHEMBL9144744 | 0.76 | KDM4E (0.49) | MCHR1KDM4EALDH1A1LMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063686-A1 | Carboxamide compounds and their use as antagonists of a human 11cby receptor | JOHNSON CHRISTOPHER NORBERT (GB) | 2004-04-01 | — | — | US | disclosed |
| EP-1305304-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF A HUMAN 11CBY RECEPTOR | SMITHKLINE BEECHAM PLC (GB) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002010146-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF A HUMAN 11CBY RECEPTOR | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063686-A1 | Carboxamide compounds and their use as antagonists of a human 11cby receptor | CNR1, GPR3, CCKAR | MCHR1 133/4885KDM4E 2413/4885ALDH1A1 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.