Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.65 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | CHRND | Q07001 | 5/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.49 |
| ▸ | CHRNG | P07510 | 1/20 | 0.49 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23086284 | 0.87 | PTPN1 (0.68) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6918308 | 0.86 | PTPN1 (0.69) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL6798151 | 0.85 | MMP2 (0.51) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4740245 | 0.84 | CHRNB2 (0.65) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL21356920 | 0.84 | CHRNB2 (0.65) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL21356921 | 0.84 | CHRNB2 (0.65) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6796552 | 0.83 | PTPN1 (0.65) | PTPN1 | |
| SCHEMBL6807834 | 0.83 | PTPN1 (0.65) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL14765234 | 0.82 | CHRNB2 (0.64) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6574908 | 0.82 | PTPN1 (0.66) | PTPN1CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040167183-A1 | Phenethylamino sulfamic acids | THE PROCTER & GAMBLE COMPANY | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167183-A1 | Phenethylamino sulfamic acids | PTPRM, PTPRS, PTPRE | PTPN1 12/4885CHRNB2 4791/4885CHRNB4 4826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.